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Female mice lacking ERβ display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy
Epilepsy is a highly prevalent and drug-refractory neurological disorder characterized by spontaneous recurrent seizures. Estrogen is identified to be proconvulsant and lowers the seizure threshold of female epilepsy. Estrogen receptor β (ERβ) has been proposed to mediate neuroprotection in epilepsy...
Autores principales: | Wang, Zhongke, Xie, Ruxin, Yang, Xiaolin, Yin, Huachun, Li, Xin, Liu, Tianyao, Ma, Yuanyuan, Gao, Junwei, Zang, Zhenle, Ruan, Ruotong, Li, Yang, Huang, Kaixuan, Chen, Qingbo, Shen, Kaifeng, Lv, Shengqing, Zhang, Chunqing, Yang, Hui, Warner, Maragret, Gustafsson, Jan-Ake, Liu, Shiyong, Fan, Xiaotang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058727/ https://www.ncbi.nlm.nih.gov/pubmed/33897900 http://dx.doi.org/10.7150/thno.56331 |
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