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Externally triggered smart drug delivery system encapsulating idarubicin shows superior kinetics and enhances tumoral drug uptake and response

Rationale: Increasing the bioavailable drug level in a tumor is the key to enhance efficacy of chemotherapy. Thermosensitive smart drug delivery systems (SDDS) in combination with local hyperthermia facilitate high local drug levels, thus improving uptake in the tumor. However, inability to rapidly...

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Detalles Bibliográficos
Autores principales: Lu, Tao, Haemmerich, Dieter, Liu, Hui, Seynhaeve, Ann L.B., van Rhoon, Gerard C., Houtsmuller, Adriaan B., ten Hagen, Timo L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058728/
https://www.ncbi.nlm.nih.gov/pubmed/33897876
http://dx.doi.org/10.7150/thno.55163