Rtpca: an R package for differential thermal proximity coaggregation analysis

SUMMARY: Rtpca is an R package implementing methods for inferring protein–protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore da...

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Detalles Bibliográficos
Autores principales: Kurzawa, Nils, Mateus, André, Savitski, Mikhail M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058776/
https://www.ncbi.nlm.nih.gov/pubmed/32717044
http://dx.doi.org/10.1093/bioinformatics/btaa682
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author Kurzawa, Nils
Mateus, André
Savitski, Mikhail M
author_facet Kurzawa, Nils
Mateus, André
Savitski, Mikhail M
author_sort Kurzawa, Nils
collection PubMed
description SUMMARY: Rtpca is an R package implementing methods for inferring protein–protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages. AVAILABILITY AND IMPLEMENTATION: Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca). SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-80587762021-04-28 Rtpca: an R package for differential thermal proximity coaggregation analysis Kurzawa, Nils Mateus, André Savitski, Mikhail M Bioinformatics Applications Notes SUMMARY: Rtpca is an R package implementing methods for inferring protein–protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages. AVAILABILITY AND IMPLEMENTATION: Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca). SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2020-07-27 /pmc/articles/PMC8058776/ /pubmed/32717044 http://dx.doi.org/10.1093/bioinformatics/btaa682 Text en © The Author(s) 2020. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Kurzawa, Nils
Mateus, André
Savitski, Mikhail M
Rtpca: an R package for differential thermal proximity coaggregation analysis
title Rtpca: an R package for differential thermal proximity coaggregation analysis
title_full Rtpca: an R package for differential thermal proximity coaggregation analysis
title_fullStr Rtpca: an R package for differential thermal proximity coaggregation analysis
title_full_unstemmed Rtpca: an R package for differential thermal proximity coaggregation analysis
title_short Rtpca: an R package for differential thermal proximity coaggregation analysis
title_sort rtpca: an r package for differential thermal proximity coaggregation analysis
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058776/
https://www.ncbi.nlm.nih.gov/pubmed/32717044
http://dx.doi.org/10.1093/bioinformatics/btaa682
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