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Efficient differentiation of human embryonic stem cells to retinal pigment epithelium under defined conditions

ABSTRACT: Age-related macular degeneration (AMD) is a highly prevalent form of blindness caused by loss death of cells of the retinal pigment epithelium (RPE). Transplantation of pluripotent stem cell (PSC)-derived RPE cells is considered a promising therapy to regenerate cell function and vision. O...

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Detalles Bibliográficos
Autores principales: Limnios, Ioannis J., Chau, Yu-Qian, Skabo, Stuart J., Surrao, Denver C., O’Neill, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058973/
https://www.ncbi.nlm.nih.gov/pubmed/33883023
http://dx.doi.org/10.1186/s13287-021-02316-7