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Choroid plexus carcinoma in an adolescent male: a case report

INTRODUCTION/BACKGROUND: Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children. CASE PRESENTATION: We report the case of an adolescent male belongi...

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Autores principales: Jameel, Patel Zeeshan, Varma, Ashish, Kumari, Pooja, Vagha, Keta, Vagha, Jayant, Damke, Sachin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058991/
https://www.ncbi.nlm.nih.gov/pubmed/33879216
http://dx.doi.org/10.1186/s13256-021-02801-w
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author Jameel, Patel Zeeshan
Varma, Ashish
Kumari, Pooja
Vagha, Keta
Vagha, Jayant
Damke, Sachin
author_facet Jameel, Patel Zeeshan
Varma, Ashish
Kumari, Pooja
Vagha, Keta
Vagha, Jayant
Damke, Sachin
author_sort Jameel, Patel Zeeshan
collection PubMed
description INTRODUCTION/BACKGROUND: Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children. CASE PRESENTATION: We report the case of an adolescent male belonging to central India who had presented with a history of persistent headache, projectile vomiting, neck stiffness, and an episode of generalized tonic-clonic seizure. Neurological examination was suggestive of a space-occupying lesion. Further neuroimaging was suggestive of a large left-sided choroid plexus carcinoma, later confirmed on pathological examination. Gross total resection was achieved and followed by radiation therapy. His recovery was satisfactory without any major events despite suffering from such a malignancy with a poor prognosis. CONCLUSION: In the absence of a global consensus on choroid plexus carcinoma management, our patient underwent a successful gross total resection and received postoperative radiotherapy. He made a satisfactory recovery with a further plan to review with gadolinium-enhanced neuroimaging at a later date. We conclude that, when possible, achieving gross total resection is of utmost importance.
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spelling pubmed-80589912021-04-21 Choroid plexus carcinoma in an adolescent male: a case report Jameel, Patel Zeeshan Varma, Ashish Kumari, Pooja Vagha, Keta Vagha, Jayant Damke, Sachin J Med Case Rep Case Report INTRODUCTION/BACKGROUND: Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children. CASE PRESENTATION: We report the case of an adolescent male belonging to central India who had presented with a history of persistent headache, projectile vomiting, neck stiffness, and an episode of generalized tonic-clonic seizure. Neurological examination was suggestive of a space-occupying lesion. Further neuroimaging was suggestive of a large left-sided choroid plexus carcinoma, later confirmed on pathological examination. Gross total resection was achieved and followed by radiation therapy. His recovery was satisfactory without any major events despite suffering from such a malignancy with a poor prognosis. CONCLUSION: In the absence of a global consensus on choroid plexus carcinoma management, our patient underwent a successful gross total resection and received postoperative radiotherapy. He made a satisfactory recovery with a further plan to review with gadolinium-enhanced neuroimaging at a later date. We conclude that, when possible, achieving gross total resection is of utmost importance. BioMed Central 2021-04-21 /pmc/articles/PMC8058991/ /pubmed/33879216 http://dx.doi.org/10.1186/s13256-021-02801-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Jameel, Patel Zeeshan
Varma, Ashish
Kumari, Pooja
Vagha, Keta
Vagha, Jayant
Damke, Sachin
Choroid plexus carcinoma in an adolescent male: a case report
title Choroid plexus carcinoma in an adolescent male: a case report
title_full Choroid plexus carcinoma in an adolescent male: a case report
title_fullStr Choroid plexus carcinoma in an adolescent male: a case report
title_full_unstemmed Choroid plexus carcinoma in an adolescent male: a case report
title_short Choroid plexus carcinoma in an adolescent male: a case report
title_sort choroid plexus carcinoma in an adolescent male: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058991/
https://www.ncbi.nlm.nih.gov/pubmed/33879216
http://dx.doi.org/10.1186/s13256-021-02801-w
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