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Polyphosphates induce amyloid fibril formation of α-synuclein in concentration-dependent distinct manners

Polyphosphates (polyPs), chains of phosphate residues found in species across nature from bacteria to mammals, were recently reported to accelerate the amyloid fibril formation of many proteins. How polyPs facilitate this process, however, remains unknown. To gain insight into their mechanisms, we u...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Keiichi, So, Masatomo, Aguirre, César, Ikenaka, Kensuke, Mochizuki, Hideki, Kawata, Yasushi, Goto, Yuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059054/ https://www.ncbi.nlm.nih.gov/pubmed/33676889 http://dx.doi.org/10.1016/j.jbc.2021.100510

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