Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

BACKGROUND: The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized to be partially mediated by the differential regul...

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Detalles Bibliográficos
Autores principales: Kasela, Silva, Ortega, Victor E., Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L., Barjaktarevic, Igor Z., Barr, R. Graham, Bleecker, Eugene R., Bowler, Russell P., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Curtis, Jeffrey L., Han, MeiLan K., Hansel, Nadia N., Hoffman, Eric A., Kaner, Robert J., Krishnan, Jerry A., Martinez, Fernando J., McDonald, Merry-Lynn N., Meyers, Deborah A., Paine, Robert, Peters, Stephen P., Castro, Mario, Denlinger, Loren C., Erzurum, Serpil C., Fahy, John V., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce D., Li, Xingnan, Moore, Wendy C., Wenzel, Sally E., Zein, Joe, Langelier, Charles, Woodruff, Prescott G., Lappalainen, Tuuli, Christenson, Stephanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059115/
https://www.ncbi.nlm.nih.gov/pubmed/33883027
http://dx.doi.org/10.1186/s13073-021-00866-2

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