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STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis
BACKGROUND: Multiple sclerosis (MS) is a debilitating neurological disease caused by autoimmune destruction of the myelin sheath. Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the pathogenesis of MS. We and others have previously demonstrated that IL-17 is critica...
Autores principales: | Zhao, Junjie, Liao, Yun, Miller-Little, William, Xiao, Jianxing, Liu, Caini, Li, Xiaoxia, Li, Xiao, Kang, Zizhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059164/ https://www.ncbi.nlm.nih.gov/pubmed/33879167 http://dx.doi.org/10.1186/s12974-021-02146-7 |
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