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Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine

Hydroxychloroquine (HCQ), the hydroxyl derivative of chloroquine (CQ), is widely used in the treatment of rheumatological conditions (systemic lupus erythematosus, rheumatoid arthritis) and is being studied for the treatment and prevention of COVID-19. Here, we investigate through mathematical model...

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Detalles Bibliográficos
Autores principales:	Whittaker, Dominic G., Capel, Rebecca A., Hendrix, Maurice, Chan, Xin Hui S., Herring, Neil, White, Nicholas J., Mirams, Gary R., Burton, Rebecca-Ann B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2021
Materias:	Organismal and Evolutionary Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059594/ https://www.ncbi.nlm.nih.gov/pubmed/33996135 http://dx.doi.org/10.1098/rsos.210235

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