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Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis
BACKGROUND: To explore the value of neutrophil count to albumin ratio (NAR) in predicting the outcomes of patients with HBV‐associated decompensated cirrhosis (HBV‐DeCi). METHODS: One hundred and fifty‐four HBV‐DeCi patients were enrolled. The 30‐day mortality was determined. Multivariate analysis w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059716/ https://www.ncbi.nlm.nih.gov/pubmed/33609049 http://dx.doi.org/10.1002/jcla.23730 |
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author | Han, Zhong He, Xia Peng, SongQing |
author_facet | Han, Zhong He, Xia Peng, SongQing |
author_sort | Han, Zhong |
collection | PubMed |
description | BACKGROUND: To explore the value of neutrophil count to albumin ratio (NAR) in predicting the outcomes of patients with HBV‐associated decompensated cirrhosis (HBV‐DeCi). METHODS: One hundred and fifty‐four HBV‐DeCi patients were enrolled. The 30‐day mortality was determined. Multivariate analysis was applied to identify risk factors for poor outcomes. Receiver operating characteristic curve analyses was performed to evaluate prognostic accuracy. RESULTS: The 30‐day mortality was 10.4%. NAR was significantly higher in non‐survivors than in survivors and was an independent predictor for unfavorable prognosis. CONCLUSIONS: The present results indicate that increased NAR is associated with poor survival in HBV‐DeCi patients and has potential for clinical application. |
format | Online Article Text |
id | pubmed-8059716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80597162021-04-23 Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis Han, Zhong He, Xia Peng, SongQing J Clin Lab Anal Research Articles BACKGROUND: To explore the value of neutrophil count to albumin ratio (NAR) in predicting the outcomes of patients with HBV‐associated decompensated cirrhosis (HBV‐DeCi). METHODS: One hundred and fifty‐four HBV‐DeCi patients were enrolled. The 30‐day mortality was determined. Multivariate analysis was applied to identify risk factors for poor outcomes. Receiver operating characteristic curve analyses was performed to evaluate prognostic accuracy. RESULTS: The 30‐day mortality was 10.4%. NAR was significantly higher in non‐survivors than in survivors and was an independent predictor for unfavorable prognosis. CONCLUSIONS: The present results indicate that increased NAR is associated with poor survival in HBV‐DeCi patients and has potential for clinical application. John Wiley and Sons Inc. 2021-02-20 /pmc/articles/PMC8059716/ /pubmed/33609049 http://dx.doi.org/10.1002/jcla.23730 Text en © 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Research Articles Han, Zhong He, Xia Peng, SongQing Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title | Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title_full | Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title_fullStr | Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title_full_unstemmed | Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title_short | Neutrophil count to albumin ratio as a prognostic indicator for HBV‐associated decompensated cirrhosis |
title_sort | neutrophil count to albumin ratio as a prognostic indicator for hbv‐associated decompensated cirrhosis |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059716/ https://www.ncbi.nlm.nih.gov/pubmed/33609049 http://dx.doi.org/10.1002/jcla.23730 |
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