Seroprevalence of CMV IgG and IgM in Korean women of childbearing age

BACKGROUND: The aim of this study was to investigate the seroprevalence of cytomegalovirus (CMV) infection using the serologic status of CMV IgG and IgM antibodies in Korean women of childbearing age. METHODS: We retrospectively reviewed CMV IgG and IgM test results from Korean women aged 15–49 year...

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Detalles Bibliográficos
Autores principales: Choi, Rihwa, Lee, Sukjung, Lee, Sang Gon, Lee, Eun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059731/
https://www.ncbi.nlm.nih.gov/pubmed/33783845
http://dx.doi.org/10.1002/jcla.23716
Descripción
Sumario:BACKGROUND: The aim of this study was to investigate the seroprevalence of cytomegalovirus (CMV) infection using the serologic status of CMV IgG and IgM antibodies in Korean women of childbearing age. METHODS: We retrospectively reviewed CMV IgG and IgM test results from Korean women aged 15–49 years who underwent testing between January 2009 and December 2019. Seroprevalence of CMV IgG and IgM by year and age was investigated. RESULTS: The study period was 11 years, and among 6837 samples tested, 95.8% were CMV IgG–positive. The seropositivity in women aged 15‐ <20 years was significantly lower (77.5%) than older age groups. Among 6837 total CMV IgG tests, 75.9% (5186) had concurrently measured CMV IgM results among which 2.4% were IgM‐positive. CONCLUSION: Considering the low CMV seropositivity of women younger than 20 years, they may need prenatal education for CMV infection.

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