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4-phenylbutyrate exerts stage-specific effects on cardiac differentiation via HDAC inhibition

4-phenylbutyrate (4-PBA), a terminal aromatic substituted fatty acid, is used widely to specifically attenuate endoplasmic reticulum (ER) stress and inhibit histone deacetylases (HDACs). In this study, we investigated the effect of 4-PBA on cardiac differentiation of mouse embryonic stem (ES) cells....

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Detalles Bibliográficos
Autores principales:	Li, Yanming, Weng, Xiaofei, Wang, Pingping, He, Zezhao, Cheng, Siya, Wang, Dongxing, Li, Xianhui, Cheng, Guanchang, Li, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059837/ https://www.ncbi.nlm.nih.gov/pubmed/33882103 http://dx.doi.org/10.1371/journal.pone.0250267

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