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Mechanisms of neuro-robotic prosthesis operation in leg amputees

Above-knee amputees suffer the lack of sensory information, even while using most advanced prostheses. Restoring intraneural sensory feedback results in functional and cognitive benefits. It is unknown how this artificial feedback, restored through a neuro-robotic leg, influences users’ sensorimotor...

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Detalles Bibliográficos
Autores principales: Valle, Giacomo, Saliji, Albulena, Fogle, Ezra, Cimolato, Andrea, Petrini, Francesco M., Raspopovic, Stanisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059925/
https://www.ncbi.nlm.nih.gov/pubmed/33883127
http://dx.doi.org/10.1126/sciadv.abd8354
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author Valle, Giacomo
Saliji, Albulena
Fogle, Ezra
Cimolato, Andrea
Petrini, Francesco M.
Raspopovic, Stanisa
author_facet Valle, Giacomo
Saliji, Albulena
Fogle, Ezra
Cimolato, Andrea
Petrini, Francesco M.
Raspopovic, Stanisa
author_sort Valle, Giacomo
collection PubMed
description Above-knee amputees suffer the lack of sensory information, even while using most advanced prostheses. Restoring intraneural sensory feedback results in functional and cognitive benefits. It is unknown how this artificial feedback, restored through a neuro-robotic leg, influences users’ sensorimotor strategies and its implications for future wearable robotics. To unveil these mechanisms, we measured gait markers of a sensorized neuroprosthesis in two leg amputees during motor tasks of different difficulty. Novel sensorimotor strategies were intuitively promoted, allowing for a higher walking speed in both tasks. We objectively quantified the augmented prosthesis’ confidence and observed the reshaping of the legs’ kinematics toward a more physiological gait. In a possible scenario of a leg amputee driving a conventional car, we showed a finer pressure estimation from the prosthesis. Users exploited different features of the neural stimulation during tasks, suggesting that a simple prosthesis sensorization could be effective for future neuro-robotic prostheses.
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spelling pubmed-80599252021-05-04 Mechanisms of neuro-robotic prosthesis operation in leg amputees Valle, Giacomo Saliji, Albulena Fogle, Ezra Cimolato, Andrea Petrini, Francesco M. Raspopovic, Stanisa Sci Adv Research Articles Above-knee amputees suffer the lack of sensory information, even while using most advanced prostheses. Restoring intraneural sensory feedback results in functional and cognitive benefits. It is unknown how this artificial feedback, restored through a neuro-robotic leg, influences users’ sensorimotor strategies and its implications for future wearable robotics. To unveil these mechanisms, we measured gait markers of a sensorized neuroprosthesis in two leg amputees during motor tasks of different difficulty. Novel sensorimotor strategies were intuitively promoted, allowing for a higher walking speed in both tasks. We objectively quantified the augmented prosthesis’ confidence and observed the reshaping of the legs’ kinematics toward a more physiological gait. In a possible scenario of a leg amputee driving a conventional car, we showed a finer pressure estimation from the prosthesis. Users exploited different features of the neural stimulation during tasks, suggesting that a simple prosthesis sensorization could be effective for future neuro-robotic prostheses. American Association for the Advancement of Science 2021-04-21 /pmc/articles/PMC8059925/ /pubmed/33883127 http://dx.doi.org/10.1126/sciadv.abd8354 Text en Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Valle, Giacomo
Saliji, Albulena
Fogle, Ezra
Cimolato, Andrea
Petrini, Francesco M.
Raspopovic, Stanisa
Mechanisms of neuro-robotic prosthesis operation in leg amputees
title Mechanisms of neuro-robotic prosthesis operation in leg amputees
title_full Mechanisms of neuro-robotic prosthesis operation in leg amputees
title_fullStr Mechanisms of neuro-robotic prosthesis operation in leg amputees
title_full_unstemmed Mechanisms of neuro-robotic prosthesis operation in leg amputees
title_short Mechanisms of neuro-robotic prosthesis operation in leg amputees
title_sort mechanisms of neuro-robotic prosthesis operation in leg amputees
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059925/
https://www.ncbi.nlm.nih.gov/pubmed/33883127
http://dx.doi.org/10.1126/sciadv.abd8354
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