XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Single-cell RNA sequencing (scRNA-seq) of tissues has revealed remarkable heterogeneity of cell types and states but does not provide information on the spatial organization of cells. To better understand how individual cells function within an anatomical space, we developed XYZeq, a workflow that e...

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Detalles Bibliográficos
Autores principales: Lee, Youjin, Bogdanoff, Derek, Wang, Yutong, Hartoularos, George C., Woo, Jonathan M., Mowery, Cody T., Nisonoff, Hunter M., Lee, David S., Sun, Yang, Lee, James, Mehdizadeh, Sadaf, Cantlon, Joshua, Shifrut, Eric, Ngyuen, David N., Roth, Theodore L., Song, Yun S., Marson, Alexander, Chow, Eric D., Ye, Chun Jimmie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059935/
https://www.ncbi.nlm.nih.gov/pubmed/33883145
http://dx.doi.org/10.1126/sciadv.abg4755

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