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Respiratory depression and analgesia by opioid drugs in freely behaving larval zebrafish

An opioid epidemic is spreading in North America with millions of opioid overdoses annually. Opioid drugs, like fentanyl, target the mu opioid receptor system and induce potentially lethal respiratory depression. The challenge in opioid research is to find a safe pain therapy with analgesic properti...

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Detalles Bibliográficos
Autores principales: Zaig, Shenhab, da Silveira Scarpellini, Carolina, Montandon, Gaspard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060028/
https://www.ncbi.nlm.nih.gov/pubmed/33720013
http://dx.doi.org/10.7554/eLife.63407

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