Homeostasis of the ER redox state subsequent to proteasome inhibition

Endoplasmic reticulum (ER) maintains within, an oxidative redox state suitable for disulfide bond formation. We monitored the ER redox dynamics subsequent to proteasome inhibition using an ER redox probe ERroGFP S4. Proteasomal inhibition initially led to oxidation of the ER, but gradually the norma...

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Detalles Bibliográficos
Autores principales: Oku, Yuki, Kariya, Masahiro, Fujimura, Takaaki, Hoseki, Jun, Sakai, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060268/
https://www.ncbi.nlm.nih.gov/pubmed/33883613
http://dx.doi.org/10.1038/s41598-021-87944-y

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