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Potent sialic acid inhibitors that target influenza A virus hemagglutinin

Eradicating influenza A virus (IAV) is difficult, due to its genetic drift and reassortment ability. As the infectious cycle is initiated by the influenza glycoprotein, hemagglutinin (HA), which mediates the binding of virions to terminal sialic acids moieties, HA is a tempting target of anti-influe...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Jen, Yeh, Cheng-Yun, Cheng, Ju-Chien, Huang, Yu-Qi, Hsu, Kai-Cheng, Lin, Yu-Feng, Lu, Chih-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060387/
https://www.ncbi.nlm.nih.gov/pubmed/33883588
http://dx.doi.org/10.1038/s41598-021-87845-0