Cargando…
Interplay Between Microglia and Alzheimer’s Disease—Focus on the Most Relevant Risks: APOE Genotype, Sex and Age
As the main immune cells of the central nervous system (CNS), microglia regulates normal development, homeostasis and general brain physiology. These functions put microglia at the forefront of CNS repair and recovery. Uncontrolled activation of microglia is related to the course of neurodegenerativ...
Autores principales: | Chen, Yanting, Hong, Tingting, Chen, Feng, Sun, Yuanhong, Wang, Yan, Cui, Lili |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060487/ https://www.ncbi.nlm.nih.gov/pubmed/33897406 http://dx.doi.org/10.3389/fnagi.2021.631827 |
Ejemplares similares
-
Triad of Risk for Late Onset Alzheimer’s: Mitochondrial Haplotype, APOE Genotype and Chromosomal Sex
por: Wang, Yiwei, et al.
Publicado: (2016) -
APOE genotype and sex modulate Alzheimer’s disease pathology in aged EFAD transgenic mice
por: Balu, Deebika, et al.
Publicado: (2023) -
Distinctive Temporal Trajectories of Alzheimer’s Disease Biomarkers According to Sex and APOE Genotype: Importance of Striatal Amyloid
por: Kim, Jun Pyo, et al.
Publicado: (2022) -
Age and sex differences in the association between APOE genotype and Alzheimer’s disease in a Taiwan Chinese population
por: Huang, Ling-Chun, et al.
Publicado: (2023) -
The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer’s Disease
por: Fernandez, Celia G., et al.
Publicado: (2019)