A strategy for complete telomere-to-telomere assembly of ciliate macronuclear genome using ultra-high coverage Nanopore data

Ciliates contain two kinds of nuclei: the germline micronucleus (MIC) and the somatic macronucleus (MAC) in a single cell. The MAC usually have fragmented chromosomes. These fragmented chromosomes, capped with telomeres at both ends, could be gene size to several megabases in length among different...

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Detalles Bibliográficos
Autores principales: Wang, Guangying, Wang, Su, Chai, Xiaocui, Zhang, Jing, Yang, Wentao, Jiang, Chuanqi, Chen, Kai, Miao, Wei, Xiong, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060514/
https://www.ncbi.nlm.nih.gov/pubmed/33897985
http://dx.doi.org/10.1016/j.csbj.2021.04.007

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