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Intercontinental transmission and local demographic expansion of SARS-CoV-2

The global outbreak of coronavirus disease 2019 (COVID-19) is greatly threatening the public health in the world. We reconstructed global transmissions and potential demographic expansions of severe acute respiratory syndrome coronavirus 2 based on genomic information. We found that intercontinental...

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Autores principales: Hu, Hong-yin, Yan, Fang, Zhu, Jia-ming, Karuno, Alex Plimo, Zhou, Wei-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060534/
https://www.ncbi.nlm.nih.gov/pubmed/33845928
http://dx.doi.org/10.1017/S0950268821000777
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author Hu, Hong-yin
Yan, Fang
Zhu, Jia-ming
Karuno, Alex Plimo
Zhou, Wei-wei
author_facet Hu, Hong-yin
Yan, Fang
Zhu, Jia-ming
Karuno, Alex Plimo
Zhou, Wei-wei
author_sort Hu, Hong-yin
collection PubMed
description The global outbreak of coronavirus disease 2019 (COVID-19) is greatly threatening the public health in the world. We reconstructed global transmissions and potential demographic expansions of severe acute respiratory syndrome coronavirus 2 based on genomic information. We found that intercontinental transmissions were rare in January and early February but drastically increased since late February. After world-wide implements of travel restrictions, the transmission frequencies decreased to a low level in April. We identified a total of 88 potential demographic expansions over the world based on the star-radiative networks and 75 of them were found in Europe and North America. The expansion numbers peaked in March and quickly dropped since April. These findings are highly concordant with epidemic reports and modelling results and highlight the significance of quarantine validity on the global spread of COVID-19. Our analyses indicate that the travel restrictions and social distancing measures are effective in containing the spread of COVID-19.
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spelling pubmed-80605342021-04-22 Intercontinental transmission and local demographic expansion of SARS-CoV-2 Hu, Hong-yin Yan, Fang Zhu, Jia-ming Karuno, Alex Plimo Zhou, Wei-wei Epidemiol Infect Original Paper The global outbreak of coronavirus disease 2019 (COVID-19) is greatly threatening the public health in the world. We reconstructed global transmissions and potential demographic expansions of severe acute respiratory syndrome coronavirus 2 based on genomic information. We found that intercontinental transmissions were rare in January and early February but drastically increased since late February. After world-wide implements of travel restrictions, the transmission frequencies decreased to a low level in April. We identified a total of 88 potential demographic expansions over the world based on the star-radiative networks and 75 of them were found in Europe and North America. The expansion numbers peaked in March and quickly dropped since April. These findings are highly concordant with epidemic reports and modelling results and highlight the significance of quarantine validity on the global spread of COVID-19. Our analyses indicate that the travel restrictions and social distancing measures are effective in containing the spread of COVID-19. Cambridge University Press 2021-04-13 /pmc/articles/PMC8060534/ /pubmed/33845928 http://dx.doi.org/10.1017/S0950268821000777 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Hu, Hong-yin
Yan, Fang
Zhu, Jia-ming
Karuno, Alex Plimo
Zhou, Wei-wei
Intercontinental transmission and local demographic expansion of SARS-CoV-2
title Intercontinental transmission and local demographic expansion of SARS-CoV-2
title_full Intercontinental transmission and local demographic expansion of SARS-CoV-2
title_fullStr Intercontinental transmission and local demographic expansion of SARS-CoV-2
title_full_unstemmed Intercontinental transmission and local demographic expansion of SARS-CoV-2
title_short Intercontinental transmission and local demographic expansion of SARS-CoV-2
title_sort intercontinental transmission and local demographic expansion of sars-cov-2
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060534/
https://www.ncbi.nlm.nih.gov/pubmed/33845928
http://dx.doi.org/10.1017/S0950268821000777
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