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Predicted regulatory SNPs reveal potential drug targets and novel companion diagnostics in psoriasis

Psoriasis is an autoimmune disease associated with interleukins, their receptors, key transcription factors and more recently, antimicrobial peptides (AMPs). Cathelicidin LL-37 is an AMP proposed to play a fundamental role in psoriasis etiology. With our proprietary software SNPClinic v.1.0, we anal...

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Detalles Bibliográficos
Autores principales: Ruiz Ramírez, Andrea Virginia, Flores-Saiffe Farías, Adolfo, Chávez Álvarez, Rocío del Carmen, Prado Montes de Oca, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060581/
https://www.ncbi.nlm.nih.gov/pubmed/33898962
http://dx.doi.org/10.1016/j.jtauto.2021.100096