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Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis
The prevention of allergic contact dermatitis hinges on maintaining the integrity of the skin barrier and responding appropriately when it is disturbed. Although intact skin is subject to sensitization via highly irritating allergens, such as poison ivy, acutely inflamed and chronically inflamed ski...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060671/ https://www.ncbi.nlm.nih.gov/pubmed/33898703 http://dx.doi.org/10.1016/j.ijwd.2020.08.004 |
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author | Nedorost, Susan Hammond, Margaret |
author_facet | Nedorost, Susan Hammond, Margaret |
author_sort | Nedorost, Susan |
collection | PubMed |
description | The prevention of allergic contact dermatitis hinges on maintaining the integrity of the skin barrier and responding appropriately when it is disturbed. Although intact skin is subject to sensitization via highly irritating allergens, such as poison ivy, acutely inflamed and chronically inflamed skin is subject to sensitization to allergens without inherent irritant potential. In the chronically inflamed state of atopic dermatitis, sensitization to proteins, such as food, also carries a risk for systemic contact dermatitis via ingestion of the allergen. Minimizing the development of irritant dermatitis is key to preventing sensitization. However, in patients with already chronically inflamed skin, reducing the use of products to the involved areas, recommending hypoallergenic products with caution, and taking measures to prevent biofilm formation are also integral to preventing sensitization to chemicals and proteins, such as food and commensal organisms. |
format | Online Article Text |
id | pubmed-8060671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-80606712021-04-23 Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis Nedorost, Susan Hammond, Margaret Int J Womens Dermatol Review The prevention of allergic contact dermatitis hinges on maintaining the integrity of the skin barrier and responding appropriately when it is disturbed. Although intact skin is subject to sensitization via highly irritating allergens, such as poison ivy, acutely inflamed and chronically inflamed skin is subject to sensitization to allergens without inherent irritant potential. In the chronically inflamed state of atopic dermatitis, sensitization to proteins, such as food, also carries a risk for systemic contact dermatitis via ingestion of the allergen. Minimizing the development of irritant dermatitis is key to preventing sensitization. However, in patients with already chronically inflamed skin, reducing the use of products to the involved areas, recommending hypoallergenic products with caution, and taking measures to prevent biofilm formation are also integral to preventing sensitization to chemicals and proteins, such as food and commensal organisms. Elsevier 2020-08-19 /pmc/articles/PMC8060671/ /pubmed/33898703 http://dx.doi.org/10.1016/j.ijwd.2020.08.004 Text en © 2020 Published by Elsevier Inc. on behalf of Women's Dermatologic Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Nedorost, Susan Hammond, Margaret Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title | Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title_full | Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title_fullStr | Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title_full_unstemmed | Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title_short | Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis |
title_sort | art of prevention: allergic sensitization through damaged skin: atopic, occupational, and stasis dermatitis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060671/ https://www.ncbi.nlm.nih.gov/pubmed/33898703 http://dx.doi.org/10.1016/j.ijwd.2020.08.004 |
work_keys_str_mv | AT nedorostsusan artofpreventionallergicsensitizationthroughdamagedskinatopicoccupationalandstasisdermatitis AT hammondmargaret artofpreventionallergicsensitizationthroughdamagedskinatopicoccupationalandstasisdermatitis |