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An unusual case of aggressive malignant spread of epithelioid hemangioendothelioma
Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm which typically originates from liver, lung, or bone. Due to the low incidence of disease, the most effective treatment is not easily studied and much of the information known about EHE has been learned through case reports and case...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060744/ https://www.ncbi.nlm.nih.gov/pubmed/33959241 http://dx.doi.org/10.1177/20363613211010858 |
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author | Hickman, Ashley D Bezerra, Evandro D Roden, Anja C Houdek, Matthew T Barlow, Jonathan D Robinson, Steven I Wahner Hendrickson, Andrea E |
author_facet | Hickman, Ashley D Bezerra, Evandro D Roden, Anja C Houdek, Matthew T Barlow, Jonathan D Robinson, Steven I Wahner Hendrickson, Andrea E |
author_sort | Hickman, Ashley D |
collection | PubMed |
description | Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm which typically originates from liver, lung, or bone. Due to the low incidence of disease, the most effective treatment is not easily studied and much of the information known about EHE has been learned through case reports and case series. In this case, we will present an uncommon form of primary soft tissue EHE with local recurrence, bone metastasis, and lymphangitic spread to the lungs leading to respiratory failure. Imaging of the chest was atypical for EHE with intraseptal thickening and hilar lymphadenopathy. Respiratory failure was progressive despite aggressive multimodal treatment. This case highlights an unusually aggressive recurrence and metastasis of primary soft tissue EHE with atypical pulmonary imaging findings. |
format | Online Article Text |
id | pubmed-8060744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-80607442021-05-05 An unusual case of aggressive malignant spread of epithelioid hemangioendothelioma Hickman, Ashley D Bezerra, Evandro D Roden, Anja C Houdek, Matthew T Barlow, Jonathan D Robinson, Steven I Wahner Hendrickson, Andrea E Rare Tumors Case Report Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm which typically originates from liver, lung, or bone. Due to the low incidence of disease, the most effective treatment is not easily studied and much of the information known about EHE has been learned through case reports and case series. In this case, we will present an uncommon form of primary soft tissue EHE with local recurrence, bone metastasis, and lymphangitic spread to the lungs leading to respiratory failure. Imaging of the chest was atypical for EHE with intraseptal thickening and hilar lymphadenopathy. Respiratory failure was progressive despite aggressive multimodal treatment. This case highlights an unusually aggressive recurrence and metastasis of primary soft tissue EHE with atypical pulmonary imaging findings. SAGE Publications 2021-04-20 /pmc/articles/PMC8060744/ /pubmed/33959241 http://dx.doi.org/10.1177/20363613211010858 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Hickman, Ashley D Bezerra, Evandro D Roden, Anja C Houdek, Matthew T Barlow, Jonathan D Robinson, Steven I Wahner Hendrickson, Andrea E An unusual case of aggressive malignant spread of epithelioid hemangioendothelioma |
title | An unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
title_full | An unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
title_fullStr | An unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
title_full_unstemmed | An unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
title_short | An unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
title_sort | unusual case of aggressive malignant spread of epithelioid
hemangioendothelioma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060744/ https://www.ncbi.nlm.nih.gov/pubmed/33959241 http://dx.doi.org/10.1177/20363613211010858 |
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