Cargando…

Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR-mediated autophagy

Diabetic liver injury is a serious complication of type 2 diabetes mellitus (T2DM), which is often irreversible in the later stage, and affects the quality of life. Autophagy serves an important role in the occurrence and development of diabetic liver injury. For example, it can improve insulin resi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yunfeng, Su, Yong, Zhang, Jie, Zhang, Yanhua, Li, Yan, Han, Yuli, Dong, Xianan, Li, Weizu, Li, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060804/ https://www.ncbi.nlm.nih.gov/pubmed/33846768 http://dx.doi.org/10.3892/mmr.2021.12076

Ejemplares similares

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
por: Li, Xuewang, et al.
Publicado: (2023)

Astragaloside IV combating liver cirrhosis through the PI3K/Akt/mTOR signaling pathway
por: Wei, Rendong, et al.
Publicado: (2019)

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis
por: Li, Ming-yong, et al.
Publicado: (2019)

Astragaloside IV alleviates heart failure by modulating Nrf-2
por: Feng, Wenxiao, et al.
Publicado: (2022)

Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice
por: Zhang, Han, et al.
Publicado: (2021)

Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis
por: Li, Zihao, et al.
Publicado: (2021)

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016)

Metformin alleviates β-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy
por: Qiu, Xiaobo, et al.
Publicado: (2021)

Astragaloside IV alleviates placental oxidative stress and inflammation in GDM mice
por: Zhou, Ling, et al.
Publicado: (2020)

Curcumin Alleviates D-Galactose-Induced Cardiomyocyte Senescence by Promoting Autophagy via the SIRT1/AMPK/mTOR Pathway
por: Yang, Lei, et al.
Publicado: (2022)

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
por: Wang, Qing, et al.
Publicado: (2023)

Ginsenoside Rg1 ameliorates aging-induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice
por: Li, Yan, et al.
Publicado: (2021)

Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
por: Yang, Yi, et al.
Publicado: (2019)

Electroacupuncture alleviates neuropathic pain caused by spared nerve injury by promoting AMPK/mTOR-mediated autophagy in dorsal root ganglion macrophage
por: Xu, Qian, et al.
Publicado: (2022)

Astragaloside IV Alleviates Infarction Induced Cardiomyocyte Injury by Improving Mitochondrial Morphology and Function
por: Zhang, Wen, et al.
Publicado: (2022)

Thymol Alleviates LPS-Induced Liver Inflammation and Apoptosis by Inhibiting NLRP3 Inflammasome Activation and the AMPK-mTOR-Autophagy Pathway
por: Dou, Xiujing, et al.
Publicado: (2022)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling
por: Sun, Dongdong, et al.
Publicado: (2020)

Ginsenoside Rg1 alleviates lipopolysaccharide-induced neuronal damage by inhibiting NLRP1 inflammasomes in HT22 cells
por: Zhang, Yaodong, et al.
Publicado: (2021)

Astragaloside IV Protects from PM2.5-Induced Lung Injury by Regulating Autophagy via Inhibition of PI3K/Akt/mTOR Signaling in vivo and in vitro
por: Pei, Caixia, et al.
Publicado: (2021)

Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells
por: Gao, Chun, et al.
Publicado: (2020)

Astragaloside IV alleviates heart failure by regulating SUMO-specific protease 1
por: Liu, Juan, et al.
Publicado: (2021)

Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis
por: Su, Shuai, et al.
Publicado: (2021)

SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy
por: Zhao, Wenyu, et al.
Publicado: (2018)

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
por: Fan, Xiaodi, et al.
Publicado: (2015)

Zhuanggu Zhitong Capsule alleviates postmenopausal osteoporosis in ovariectomized rats by regulating autophagy through AMPK/mTOR signaling pathway
por: Men, Zhitao, et al.
Publicado: (2022)

Astragaloside IV improves renal function and alleviates renal damage and inflammation in rats with chronic glomerulonephritis
por: ZHANG, Dong, et al.
Publicado: (2022)

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo
por: Wu, Suxiao, et al.
Publicado: (2019)

Astragaloside IV alleviates heart failure by promoting angiogenesis through the JAK-STAT3 pathway
por: Sui, Yan-Bo, et al.
Publicado: (2019)

Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice
por: Han, Yuli, et al.
Publicado: (2022)

Astragaloside IV alleviates senescence of vascular smooth muscle cells through activating Parkin-mediated mitophagy
por: Li, Huijun, et al.
Publicado: (2022)

Hydrogen sulphide exacerbates acute pancreatitis by over‐activating autophagy via AMPK/mTOR pathway
por: Ji, Liang, et al.
Publicado: (2016)

Anticancer effects and mechanisms of astragaloside-IV
por: Zhou, Liangxing, et al.
Publicado: (2022)

Cytotoxicity and Autophagy Induced by Ivermectin via AMPK/mTOR Signaling Pathway in RAW264.7 Cells
por: Wang, Xiang, et al.
Publicado: (2023)

Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
por: Zheng, Xiangjin, et al.
Publicado: (2021)

[Corrigendum] Astragaloside IV alleviates heart failure by regulating SUMO‑specific protease 1
por: Liu, Juan, et al.
Publicado: (2023)

The protective roles of allicin on type 1 diabetes mellitus through AMPK/mTOR mediated autophagy pathway
por: Qian, Rengcheng, et al.
Publicado: (2023)

Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer
por: Hu, Changxiao, et al.
Publicado: (2021)

Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
por: Xu, Fei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_56riq731a66t29oleb7pgluiqt