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An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel

AIM: Investigation and evaluation of remineralization potential of functionalized tricalcium phosphate paste (fTCP) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACPF) paste on artificially created white spot lesion on human primary and permanent enamel through scanning electron microsc...

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Autores principales: Bhadoria, Neha, Gunwal, Mohit K, Kukreja, Rinky, Maran, Satish, Devendrappa, Shashikiran N, Singla, Shilpy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060932/
https://www.ncbi.nlm.nih.gov/pubmed/33976478
http://dx.doi.org/10.5005/jp-journals-10005-1813
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author Bhadoria, Neha
Gunwal, Mohit K
Kukreja, Rinky
Maran, Satish
Devendrappa, Shashikiran N
Singla, Shilpy
author_facet Bhadoria, Neha
Gunwal, Mohit K
Kukreja, Rinky
Maran, Satish
Devendrappa, Shashikiran N
Singla, Shilpy
author_sort Bhadoria, Neha
collection PubMed
description AIM: Investigation and evaluation of remineralization potential of functionalized tricalcium phosphate paste (fTCP) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACPF) paste on artificially created white spot lesion on human primary and permanent enamel through scanning electron microscopy and microhardness assessment. MATERIALS AND METHODS: Sixty freshly extracted primary and permanent teeth were selected and artificial white spot lesion were created by using standardized demineralizing solution. Remineralization was carried out using the test pastes. The assessment of demineralization and remineralization was done through a scanning electron microscope and microhardness assessment. RESULTS: Among the three groups, fTCP shows significantly higher increase in mean microhardness (p < 0.001) through ANOVA and the LSD post hoc test when compared to CPP-ACPF and control group. Also, the unpaired t-test showed that mean change in microhardness in permanent teeth was significantly higher than primary teeth in different time intervals for both experimental groups. Surface morphology was assessed through a scanning electron microscope. CONCLUSION: Based on the results of the current study, f-TCP showed comparatively more remineralization potential than CPP-ACP with fluoride. HOW TO CITE THIS ARTICLE: Bhadoria N, Gunwal MK, Kukreja R, et al. An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel. Int J Clin Pediatr Dent 2020;13(6):579–584.
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spelling pubmed-80609322021-05-10 An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel Bhadoria, Neha Gunwal, Mohit K Kukreja, Rinky Maran, Satish Devendrappa, Shashikiran N Singla, Shilpy Int J Clin Pediatr Dent Original Article AIM: Investigation and evaluation of remineralization potential of functionalized tricalcium phosphate paste (fTCP) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACPF) paste on artificially created white spot lesion on human primary and permanent enamel through scanning electron microscopy and microhardness assessment. MATERIALS AND METHODS: Sixty freshly extracted primary and permanent teeth were selected and artificial white spot lesion were created by using standardized demineralizing solution. Remineralization was carried out using the test pastes. The assessment of demineralization and remineralization was done through a scanning electron microscope and microhardness assessment. RESULTS: Among the three groups, fTCP shows significantly higher increase in mean microhardness (p < 0.001) through ANOVA and the LSD post hoc test when compared to CPP-ACPF and control group. Also, the unpaired t-test showed that mean change in microhardness in permanent teeth was significantly higher than primary teeth in different time intervals for both experimental groups. Surface morphology was assessed through a scanning electron microscope. CONCLUSION: Based on the results of the current study, f-TCP showed comparatively more remineralization potential than CPP-ACP with fluoride. HOW TO CITE THIS ARTICLE: Bhadoria N, Gunwal MK, Kukreja R, et al. An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel. Int J Clin Pediatr Dent 2020;13(6):579–584. Jaypee Brothers Medical Publishers 2020 /pmc/articles/PMC8060932/ /pubmed/33976478 http://dx.doi.org/10.5005/jp-journals-10005-1813 Text en Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Article
Bhadoria, Neha
Gunwal, Mohit K
Kukreja, Rinky
Maran, Satish
Devendrappa, Shashikiran N
Singla, Shilpy
An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title_full An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title_fullStr An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title_full_unstemmed An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title_short An In Vitro Evaluation of Remineralization Potential of Functionalized Tricalcium Phosphate Paste and CPP-ACPF on Artificial White Spot Lesion in Primary and Permanent Enamel
title_sort in vitro evaluation of remineralization potential of functionalized tricalcium phosphate paste and cpp-acpf on artificial white spot lesion in primary and permanent enamel
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060932/
https://www.ncbi.nlm.nih.gov/pubmed/33976478
http://dx.doi.org/10.5005/jp-journals-10005-1813
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