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Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19

In the present study, the magnetic field induced self-assembly processes of magnetic microparticles in an aqueous liquid (the pure magnetic fluid) and nonmagnetic microparticles in ferrofluid (the inverse magnetic fluid) are experimentally investigated. The microparticles are formed into chain-like...

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Autores principales: Li, Xiang, Dong, Zhi-Qiang, Yu, Peng, Wang, Lian-Ping, Niu, Xiao-Dong, Yamaguchi, Hiroshi, Li, De-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060970/
https://www.ncbi.nlm.nih.gov/pubmed/33897247
http://dx.doi.org/10.1063/5.0048123
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author Li, Xiang
Dong, Zhi-Qiang
Yu, Peng
Wang, Lian-Ping
Niu, Xiao-Dong
Yamaguchi, Hiroshi
Li, De-Cai
author_facet Li, Xiang
Dong, Zhi-Qiang
Yu, Peng
Wang, Lian-Ping
Niu, Xiao-Dong
Yamaguchi, Hiroshi
Li, De-Cai
author_sort Li, Xiang
collection PubMed
description In the present study, the magnetic field induced self-assembly processes of magnetic microparticles in an aqueous liquid (the pure magnetic fluid) and nonmagnetic microparticles in ferrofluid (the inverse magnetic fluid) are experimentally investigated. The microparticles are formed into chain-like microstructures in both the pure magnetic fluid and the inverse magnetic fluid by applying the external magnetic field. The fluorescence parameters of these self-assembled chain-like microstructures are measured and compared to those without the effect of magnetic field. It is found that the fluorescence in the pure magnetic fluid is weakened, because the scattering and illuminating areas are reduced in the microstructures. On the contrary, the fluorescence in the inverse magnetic fluid is enhanced, because more fluorescent nonmagnetic microparticles are enriched and become detectable under the effect of the magnetic dipole force and the magnetic levitational force, and their unnecessary scattering can be absorbed by the surrounding ferrofluid. The average enhancement of the fluorescence area ratio in the inverse magnetic fluid with 3 μm nonmagnetic microparticles reaches 112.92%. The present work shows that the inverse magnetic fluid has advantages such as low cost, no scattering effect, stable fluorescence intensity, and relatively low magnetic resistance. In the end, a prototype design for the novel detection of coronavirus disease 2019 based on the magnetic field induced self-assembly in the inverse magnetic fluid is proposed, which could support the epidemic prevention and control.
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spelling pubmed-80609702021-04-22 Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19 Li, Xiang Dong, Zhi-Qiang Yu, Peng Wang, Lian-Ping Niu, Xiao-Dong Yamaguchi, Hiroshi Li, De-Cai Phys Fluids (1994) ARTICLES In the present study, the magnetic field induced self-assembly processes of magnetic microparticles in an aqueous liquid (the pure magnetic fluid) and nonmagnetic microparticles in ferrofluid (the inverse magnetic fluid) are experimentally investigated. The microparticles are formed into chain-like microstructures in both the pure magnetic fluid and the inverse magnetic fluid by applying the external magnetic field. The fluorescence parameters of these self-assembled chain-like microstructures are measured and compared to those without the effect of magnetic field. It is found that the fluorescence in the pure magnetic fluid is weakened, because the scattering and illuminating areas are reduced in the microstructures. On the contrary, the fluorescence in the inverse magnetic fluid is enhanced, because more fluorescent nonmagnetic microparticles are enriched and become detectable under the effect of the magnetic dipole force and the magnetic levitational force, and their unnecessary scattering can be absorbed by the surrounding ferrofluid. The average enhancement of the fluorescence area ratio in the inverse magnetic fluid with 3 μm nonmagnetic microparticles reaches 112.92%. The present work shows that the inverse magnetic fluid has advantages such as low cost, no scattering effect, stable fluorescence intensity, and relatively low magnetic resistance. In the end, a prototype design for the novel detection of coronavirus disease 2019 based on the magnetic field induced self-assembly in the inverse magnetic fluid is proposed, which could support the epidemic prevention and control. AIP Publishing LLC 2021-04 2021-04-06 /pmc/articles/PMC8060970/ /pubmed/33897247 http://dx.doi.org/10.1063/5.0048123 Text en © 2021 Author(s) Published under license by AIP Publishing. 1070-6631/2021/33(4)/042004/15/$30.00 https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle ARTICLES
Li, Xiang
Dong, Zhi-Qiang
Yu, Peng
Wang, Lian-Ping
Niu, Xiao-Dong
Yamaguchi, Hiroshi
Li, De-Cai
Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title_full Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title_fullStr Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title_full_unstemmed Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title_short Effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for COVID-19
title_sort effect of self-assembly on fluorescence in magnetic multiphase flows and its application on the novel detection for covid-19
topic ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060970/
https://www.ncbi.nlm.nih.gov/pubmed/33897247
http://dx.doi.org/10.1063/5.0048123
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