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A new surgical method of treatment spontaneous intracranial hemorrhage
OBJECTIVE: This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH). METHODS: This retrospective study included clinical data from 260 patients with spontaneous supratentorial ICH who received neuroendoscopic hematoma remova...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060980/ https://www.ncbi.nlm.nih.gov/pubmed/33976932 http://dx.doi.org/10.1515/tnsci-2020-0164 |
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author | Du, Ning Wang, Xinjun Zhang, Xuyang Xie, Jingwei Zhou, Shaolong Wu, Yuehui Guo, Yongkun |
author_facet | Du, Ning Wang, Xinjun Zhang, Xuyang Xie, Jingwei Zhou, Shaolong Wu, Yuehui Guo, Yongkun |
author_sort | Du, Ning |
collection | PubMed |
description | OBJECTIVE: This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH). METHODS: This retrospective study included clinical data from 260 patients with spontaneous supratentorial ICH who received neuroendoscopic hematoma removal. Patients were separated into groups based on the surgery method they received: DTI-assisted neuroendoscopy (69 cases) and standard neuroendoscopy (191 cases). All patients were followed up for 6 months. Multivariate logistic regression analyzed the risk factors affecting the prognosis of patients. The outcomes of the two groups were compared using Kaplan–Meier survival curves. RESULTS: The prognostic modified Rankin Scale (mRS) score was significantly better (P = 0.027) in the DTI-assisted neuroendoscopy group than in the standard neuroendoscopy group. Logistic regression analysis showed that DTI-assisted neuroendoscopy is an independent protective factor for a favorable outcome (model 1: odds ratio [OR] = 0.42, P = 0.015; model 2: OR = 0.40, P = 0.013). Kaplan–Meier survival curves were used to show that the median time for a favorable outcome was 66 days (95% confidence interval [CI] = 48.50–83.50 days) in the DTI-assisted neuroendoscopy group and 104 days (95% CI = 75.55–132.45 days) in the standard neuroendoscopy group. Log-rank testing showed that the DTI-assisted neuroendoscopy group had a lower pulmonary infection rate (χ (2) = 4.706, P = 0.030) and a better prognosis (χ (2) = 5.223, P = 0.022) than the standard neuroendoscopy group. The survival rate did not differ significantly between the DTI-assisted neuroendoscopy group and the standard neuroendoscopy group (P > 0.05). CONCLUSIONS: The use of DTI in neuroendoscopic hematoma removal can significantly improve neurological function outcomes in patients, but it does not significantly affect the mortality of patients. |
format | Online Article Text |
id | pubmed-8060980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | De Gruyter |
record_format | MEDLINE/PubMed |
spelling | pubmed-80609802021-05-10 A new surgical method of treatment spontaneous intracranial hemorrhage Du, Ning Wang, Xinjun Zhang, Xuyang Xie, Jingwei Zhou, Shaolong Wu, Yuehui Guo, Yongkun Transl Neurosci Research Article OBJECTIVE: This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH). METHODS: This retrospective study included clinical data from 260 patients with spontaneous supratentorial ICH who received neuroendoscopic hematoma removal. Patients were separated into groups based on the surgery method they received: DTI-assisted neuroendoscopy (69 cases) and standard neuroendoscopy (191 cases). All patients were followed up for 6 months. Multivariate logistic regression analyzed the risk factors affecting the prognosis of patients. The outcomes of the two groups were compared using Kaplan–Meier survival curves. RESULTS: The prognostic modified Rankin Scale (mRS) score was significantly better (P = 0.027) in the DTI-assisted neuroendoscopy group than in the standard neuroendoscopy group. Logistic regression analysis showed that DTI-assisted neuroendoscopy is an independent protective factor for a favorable outcome (model 1: odds ratio [OR] = 0.42, P = 0.015; model 2: OR = 0.40, P = 0.013). Kaplan–Meier survival curves were used to show that the median time for a favorable outcome was 66 days (95% confidence interval [CI] = 48.50–83.50 days) in the DTI-assisted neuroendoscopy group and 104 days (95% CI = 75.55–132.45 days) in the standard neuroendoscopy group. Log-rank testing showed that the DTI-assisted neuroendoscopy group had a lower pulmonary infection rate (χ (2) = 4.706, P = 0.030) and a better prognosis (χ (2) = 5.223, P = 0.022) than the standard neuroendoscopy group. The survival rate did not differ significantly between the DTI-assisted neuroendoscopy group and the standard neuroendoscopy group (P > 0.05). CONCLUSIONS: The use of DTI in neuroendoscopic hematoma removal can significantly improve neurological function outcomes in patients, but it does not significantly affect the mortality of patients. De Gruyter 2021-04-20 /pmc/articles/PMC8060980/ /pubmed/33976932 http://dx.doi.org/10.1515/tnsci-2020-0164 Text en © 2021 Ning Du et al., published by De Gruyter https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License. |
spellingShingle | Research Article Du, Ning Wang, Xinjun Zhang, Xuyang Xie, Jingwei Zhou, Shaolong Wu, Yuehui Guo, Yongkun A new surgical method of treatment spontaneous intracranial hemorrhage |
title | A new surgical method of treatment spontaneous intracranial hemorrhage |
title_full | A new surgical method of treatment spontaneous intracranial hemorrhage |
title_fullStr | A new surgical method of treatment spontaneous intracranial hemorrhage |
title_full_unstemmed | A new surgical method of treatment spontaneous intracranial hemorrhage |
title_short | A new surgical method of treatment spontaneous intracranial hemorrhage |
title_sort | new surgical method of treatment spontaneous intracranial hemorrhage |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060980/ https://www.ncbi.nlm.nih.gov/pubmed/33976932 http://dx.doi.org/10.1515/tnsci-2020-0164 |
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