Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer’s disease risk

Alzheimer’s disease (AD) is the most common type of dementia, affecting millions of people worldwide; however, no disease-modifying treatments are currently available. Genome-wide association studies (GWASs) have identified more than 40 loci associated with AD risk. However, most of the disease-asso...

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Detalles Bibliográficos
Autores principales: Novikova, Gloriia, Andrews, Shea J., Renton, Alan E., Marcora, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061035/
https://www.ncbi.nlm.nih.gov/pubmed/33882988
http://dx.doi.org/10.1186/s13024-021-00449-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061035/
https://www.ncbi.nlm.nih.gov/pubmed/33882988
http://dx.doi.org/10.1186/s13024-021-00449-0

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