Cargando…

Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis

BACKGROUND: The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse events. The objective of this systematic review and meta-analysis is to determine...

Descripción completa

Detalles Bibliográficos
Autores principales: Saripella, Aparna, Wasef, Sara, Nagappa, Mahesh, Riazi, Sheila, Englesakis, Marina, Wong, Jean, Chung, Frances
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061210/
https://www.ncbi.nlm.nih.gov/pubmed/33888071
http://dx.doi.org/10.1186/s12871-021-01337-2
_version_ 1783681520063479808
author Saripella, Aparna
Wasef, Sara
Nagappa, Mahesh
Riazi, Sheila
Englesakis, Marina
Wong, Jean
Chung, Frances
author_facet Saripella, Aparna
Wasef, Sara
Nagappa, Mahesh
Riazi, Sheila
Englesakis, Marina
Wong, Jean
Chung, Frances
author_sort Saripella, Aparna
collection PubMed
description BACKGROUND: The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse events. The objective of this systematic review and meta-analysis is to determine whether the comprehensive geriatric care models improved clinical outcomes, particularly in decreasing the prevalence of delirium and length of hospital stay (LOS) in elderly surgical patients. METHOD: We searched Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Emcare Nursing, Web of Science, Scopus, CINAHL, ClinicalTrials. Gov, and ICTRP between 2009 to January 23, 2020. We included studies on geriatric care models in elderly patients (≥60 years) undergoing elective, non-cardiac high-risk surgery. The outcomes were the prevalence of delirium, LOS, rates of 30-days readmission, and 30-days mortality. We used the Cochrane Review Manager Version 5.3. to estimate the pooled Odds Ratio (OR) and Mean Difference (MD) using random effect model analysis. RESULTS: Eleven studies were included with 2672 patients [Randomized Controlled Trials (RCTs): 4; Non-Randomized Controlled Trials (Non-RCTs): 7]. Data pooled from six studies showed that there was no significant difference in the prevalence of delirium between the intervention and control groups: 13.8% vs 15.9% (OR: 0.76; 95% CI: 0.30–1.96; p = 0.57). Similarly, there were no significant differences in the LOS (MD: -0.55; 95% CI: − 2.28, 1.18; p = 0.53), 30-day readmission (12.1% vs. 14.3%; OR: 1.09; 95% CI: 0.67–1.77; p = 0.73), and 30-day mortality (3.2% vs. 2.1%; OR: 1.34; 95% CI: 0.66–2.69; p = 0.42). The quality of evidence was very low. CONCLUSIONS: The geriatric care models involved pre-operative comprehensive geriatric assessment, and intervention tools to address cognition, frailty, and functional status. In non-cardiac high-risk surgeries, these care models did not show any significant difference in the prevalence of delirium, LOS, 30-days readmission rates, and 30-day mortality in geriatric patients. Further RCTs are warranted to evaluate these models on the postoperative outcomes. TRIAL REGISTRATION: PROSPERO registration number - CRD42020181779. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-021-01337-2.
format Online
Article
Text
id pubmed-8061210
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-80612102021-04-22 Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis Saripella, Aparna Wasef, Sara Nagappa, Mahesh Riazi, Sheila Englesakis, Marina Wong, Jean Chung, Frances BMC Anesthesiol Research Article BACKGROUND: The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse events. The objective of this systematic review and meta-analysis is to determine whether the comprehensive geriatric care models improved clinical outcomes, particularly in decreasing the prevalence of delirium and length of hospital stay (LOS) in elderly surgical patients. METHOD: We searched Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Emcare Nursing, Web of Science, Scopus, CINAHL, ClinicalTrials. Gov, and ICTRP between 2009 to January 23, 2020. We included studies on geriatric care models in elderly patients (≥60 years) undergoing elective, non-cardiac high-risk surgery. The outcomes were the prevalence of delirium, LOS, rates of 30-days readmission, and 30-days mortality. We used the Cochrane Review Manager Version 5.3. to estimate the pooled Odds Ratio (OR) and Mean Difference (MD) using random effect model analysis. RESULTS: Eleven studies were included with 2672 patients [Randomized Controlled Trials (RCTs): 4; Non-Randomized Controlled Trials (Non-RCTs): 7]. Data pooled from six studies showed that there was no significant difference in the prevalence of delirium between the intervention and control groups: 13.8% vs 15.9% (OR: 0.76; 95% CI: 0.30–1.96; p = 0.57). Similarly, there were no significant differences in the LOS (MD: -0.55; 95% CI: − 2.28, 1.18; p = 0.53), 30-day readmission (12.1% vs. 14.3%; OR: 1.09; 95% CI: 0.67–1.77; p = 0.73), and 30-day mortality (3.2% vs. 2.1%; OR: 1.34; 95% CI: 0.66–2.69; p = 0.42). The quality of evidence was very low. CONCLUSIONS: The geriatric care models involved pre-operative comprehensive geriatric assessment, and intervention tools to address cognition, frailty, and functional status. In non-cardiac high-risk surgeries, these care models did not show any significant difference in the prevalence of delirium, LOS, 30-days readmission rates, and 30-day mortality in geriatric patients. Further RCTs are warranted to evaluate these models on the postoperative outcomes. TRIAL REGISTRATION: PROSPERO registration number - CRD42020181779. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12871-021-01337-2. BioMed Central 2021-04-22 /pmc/articles/PMC8061210/ /pubmed/33888071 http://dx.doi.org/10.1186/s12871-021-01337-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Saripella, Aparna
Wasef, Sara
Nagappa, Mahesh
Riazi, Sheila
Englesakis, Marina
Wong, Jean
Chung, Frances
Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title_full Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title_fullStr Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title_full_unstemmed Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title_short Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
title_sort effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061210/
https://www.ncbi.nlm.nih.gov/pubmed/33888071
http://dx.doi.org/10.1186/s12871-021-01337-2
work_keys_str_mv AT saripellaaparna effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT wasefsara effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT nagappamahesh effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT riazisheila effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT englesakismarina effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT wongjean effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis
AT chungfrances effectsofcomprehensivegeriatriccaremodelsonpostoperativeoutcomesingeriatricsurgicalpatientsasystematicreviewandmetaanalysis