Cargando…
Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries
AIMS: Cognitive deficits are an important factor in the pathogenesis of psychosis. Subjective cognitive complaints (SCCs) are often considered to be a precursor of objective cognitive deficits, but there are no studies specifically on SCC and psychotic experiences (PE). Thus, we assessed the associa...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061242/ https://www.ncbi.nlm.nih.gov/pubmed/30585571 http://dx.doi.org/10.1017/S2045796018000744 |
_version_ | 1783681526254272512 |
---|---|
author | Koyanagi, A. Stubbs, B. Lara, E. Veronese, N. Vancampfort, D. Smith, L. Haro, J. M. Oh, H. DeVylder, J. E. |
author_facet | Koyanagi, A. Stubbs, B. Lara, E. Veronese, N. Vancampfort, D. Smith, L. Haro, J. M. Oh, H. DeVylder, J. E. |
author_sort | Koyanagi, A. |
collection | PubMed |
description | AIMS: Cognitive deficits are an important factor in the pathogenesis of psychosis. Subjective cognitive complaints (SCCs) are often considered to be a precursor of objective cognitive deficits, but there are no studies specifically on SCC and psychotic experiences (PE). Thus, we assessed the association between SCC and PE using data from 48 low- and middle-income countries. METHODS: Community-based cross-sectional data of the World Health Survey were analysed. Two questions on subjective memory and learning complaints in the past 30 days were used to create a SCC scale ranging from 0 to 10 with higher scores representing more severe SCC. The Composite International Diagnostic Interview was used to identify past 12-month PE. Multivariable logistic regression and mediation analyses were performed. RESULTS: The final sample consisted of 224 842 adults aged ⩾18 years [mean (SD) age 38.3 (16.0) years; 49.3% males]. After adjustment for sociodemographic factors, a one-unit increase in the SCC scale was associated with a 1.17 (95% CI 1.16–1.18) times higher odds for PE in the overall sample, with this association being more pronounced in younger individuals: age 18–44 years OR = 1.19 (95% CI 1.17–1.20); 45–64 years OR = 1.15 (95% CI 1.12–1.17); ⩾65 years OR = 1.14 (95% CI 1.09–1.19). Collectively, other mental health conditions (perceived stress, depression, anxiety, sleep problems) explained 43.4% of this association, and chronic physical conditions partially explained the association but to a lesser extent (11.8%). CONCLUSIONS: SCC were associated with PE. Future longitudinal studies are needed to understand temporal associations and causal inferences, while the utility of SCC as a risk marker for psychosis especially for young adults should be scrutinised. |
format | Online Article Text |
id | pubmed-8061242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-80612422021-05-04 Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries Koyanagi, A. Stubbs, B. Lara, E. Veronese, N. Vancampfort, D. Smith, L. Haro, J. M. Oh, H. DeVylder, J. E. Epidemiol Psychiatr Sci Original Articles AIMS: Cognitive deficits are an important factor in the pathogenesis of psychosis. Subjective cognitive complaints (SCCs) are often considered to be a precursor of objective cognitive deficits, but there are no studies specifically on SCC and psychotic experiences (PE). Thus, we assessed the association between SCC and PE using data from 48 low- and middle-income countries. METHODS: Community-based cross-sectional data of the World Health Survey were analysed. Two questions on subjective memory and learning complaints in the past 30 days were used to create a SCC scale ranging from 0 to 10 with higher scores representing more severe SCC. The Composite International Diagnostic Interview was used to identify past 12-month PE. Multivariable logistic regression and mediation analyses were performed. RESULTS: The final sample consisted of 224 842 adults aged ⩾18 years [mean (SD) age 38.3 (16.0) years; 49.3% males]. After adjustment for sociodemographic factors, a one-unit increase in the SCC scale was associated with a 1.17 (95% CI 1.16–1.18) times higher odds for PE in the overall sample, with this association being more pronounced in younger individuals: age 18–44 years OR = 1.19 (95% CI 1.17–1.20); 45–64 years OR = 1.15 (95% CI 1.12–1.17); ⩾65 years OR = 1.14 (95% CI 1.09–1.19). Collectively, other mental health conditions (perceived stress, depression, anxiety, sleep problems) explained 43.4% of this association, and chronic physical conditions partially explained the association but to a lesser extent (11.8%). CONCLUSIONS: SCC were associated with PE. Future longitudinal studies are needed to understand temporal associations and causal inferences, while the utility of SCC as a risk marker for psychosis especially for young adults should be scrutinised. Cambridge University Press 2018-12-26 /pmc/articles/PMC8061242/ /pubmed/30585571 http://dx.doi.org/10.1017/S2045796018000744 Text en © The Author(s) 2018 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Koyanagi, A. Stubbs, B. Lara, E. Veronese, N. Vancampfort, D. Smith, L. Haro, J. M. Oh, H. DeVylder, J. E. Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title | Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title_full | Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title_fullStr | Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title_full_unstemmed | Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title_short | Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
title_sort | psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061242/ https://www.ncbi.nlm.nih.gov/pubmed/30585571 http://dx.doi.org/10.1017/S2045796018000744 |
work_keys_str_mv | AT koyanagia psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT stubbsb psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT larae psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT veronesen psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT vancampfortd psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT smithl psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT harojm psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT ohh psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries AT devylderje psychoticexperiencesandsubjectivecognitivecomplaintsamong224842peoplein48lowandmiddleincomecountries |