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Sphingomyelin liposome bearing whole Leishmania lysate antigens induce strong Th2 immune response in BALB/c mice

OBJECTIVE(S): Whole Leishmania lysate antigens (WLL) has been shown to be effective to tackle leishmaniasis in murine models. Although liposomes can be considered as promising vaccines, the activity of phospholipase-A (PLA) in WLL, breeds difficulties to preparing stable liposomal WLL. One strategy...

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Detalles Bibliográficos
Autores principales: Biari, Nazanin, Alavizadeh, Seyedeh Hoda, Chavoshian, Omid, Abbasi, Azam, Saberi, Zahra, Jalali, Seyed Amir, Khamesipoure, Ali, Jaafari, Mahmoud Reza, Badiee, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061322/
https://www.ncbi.nlm.nih.gov/pubmed/33953862
http://dx.doi.org/10.22038/IJBMS.2020.50471.11496