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Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061619/ https://www.ncbi.nlm.nih.gov/pubmed/33912428 http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19 |
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author | Pandey, Vijayendra Kumar, Deepak Nisha, Swet Gupta, Alok Kumar Verma, Tanya Kumari, Ayusha |
author_facet | Pandey, Vijayendra Kumar, Deepak Nisha, Swet Gupta, Alok Kumar Verma, Tanya Kumari, Ayusha |
author_sort | Pandey, Vijayendra |
collection | PubMed |
description | CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding. MATERIALS AND METHODS: Sixty patients in the age group of 20–60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically. RESULTS: The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A (P < 0.001) as compared to Group B. CONCLUSION: Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP. |
format | Online Article Text |
id | pubmed-8061619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-80616192021-04-27 Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study Pandey, Vijayendra Kumar, Deepak Nisha, Swet Gupta, Alok Kumar Verma, Tanya Kumari, Ayusha Int J Appl Basic Med Res Original Article CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding. MATERIALS AND METHODS: Sixty patients in the age group of 20–60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically. RESULTS: The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A (P < 0.001) as compared to Group B. CONCLUSION: Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP. Wolters Kluwer - Medknow 2021 2021-04-08 /pmc/articles/PMC8061619/ /pubmed/33912428 http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19 Text en Copyright: © 2021 International Journal of Applied and Basic Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Pandey, Vijayendra Kumar, Deepak Nisha, Swet Gupta, Alok Kumar Verma, Tanya Kumari, Ayusha Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title | Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title_full | Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title_fullStr | Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title_full_unstemmed | Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title_short | Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study |
title_sort | evaluation of anti-plaque and anti-inflammatory effects of oral curcumin gel as adjunct to scaling and root planing: a clinical study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061619/ https://www.ncbi.nlm.nih.gov/pubmed/33912428 http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19 |
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