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Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study

CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP)...

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Autores principales: Pandey, Vijayendra, Kumar, Deepak, Nisha, Swet, Gupta, Alok Kumar, Verma, Tanya, Kumari, Ayusha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061619/
https://www.ncbi.nlm.nih.gov/pubmed/33912428
http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19
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author Pandey, Vijayendra
Kumar, Deepak
Nisha, Swet
Gupta, Alok Kumar
Verma, Tanya
Kumari, Ayusha
author_facet Pandey, Vijayendra
Kumar, Deepak
Nisha, Swet
Gupta, Alok Kumar
Verma, Tanya
Kumari, Ayusha
author_sort Pandey, Vijayendra
collection PubMed
description CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding. MATERIALS AND METHODS: Sixty patients in the age group of 20–60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically. RESULTS: The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A (P < 0.001) as compared to Group B. CONCLUSION: Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP.
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spelling pubmed-80616192021-04-27 Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study Pandey, Vijayendra Kumar, Deepak Nisha, Swet Gupta, Alok Kumar Verma, Tanya Kumari, Ayusha Int J Appl Basic Med Res Original Article CONTEXT: The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding. MATERIALS AND METHODS: Sixty patients in the age group of 20–60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically. RESULTS: The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A (P < 0.001) as compared to Group B. CONCLUSION: Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP. Wolters Kluwer - Medknow 2021 2021-04-08 /pmc/articles/PMC8061619/ /pubmed/33912428 http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19 Text en Copyright: © 2021 International Journal of Applied and Basic Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pandey, Vijayendra
Kumar, Deepak
Nisha, Swet
Gupta, Alok Kumar
Verma, Tanya
Kumari, Ayusha
Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title_full Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title_fullStr Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title_full_unstemmed Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title_short Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study
title_sort evaluation of anti-plaque and anti-inflammatory effects of oral curcumin gel as adjunct to scaling and root planing: a clinical study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061619/
https://www.ncbi.nlm.nih.gov/pubmed/33912428
http://dx.doi.org/10.4103/ijabmr.IJABMR_391_19
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