Driving forces in the origins of life

What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins...

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Detalles Bibliográficos
Autores principales: Dill, K. A., Agozzino, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061700/
https://www.ncbi.nlm.nih.gov/pubmed/33529553
http://dx.doi.org/10.1098/rsob.200324
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author Dill, K. A.
Agozzino, L.
author_facet Dill, K. A.
Agozzino, L.
author_sort Dill, K. A.
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description What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins-first’ world gives plausible mechanisms. We note the importance of hydrophobic and polar compositions of matter in these advances.
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spelling pubmed-80617002021-05-14 Driving forces in the origins of life Dill, K. A. Agozzino, L. Open Biol Review What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins-first’ world gives plausible mechanisms. We note the importance of hydrophobic and polar compositions of matter in these advances. The Royal Society 2021-02-03 /pmc/articles/PMC8061700/ /pubmed/33529553 http://dx.doi.org/10.1098/rsob.200324 Text en © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Review
Dill, K. A.
Agozzino, L.
Driving forces in the origins of life
title Driving forces in the origins of life
title_full Driving forces in the origins of life
title_fullStr Driving forces in the origins of life
title_full_unstemmed Driving forces in the origins of life
title_short Driving forces in the origins of life
title_sort driving forces in the origins of life
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8061700/
https://www.ncbi.nlm.nih.gov/pubmed/33529553
http://dx.doi.org/10.1098/rsob.200324
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