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Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ)
INTRODUCTION: Currently available screening questionnaires for Autism spectrum disorders were tested in developed countries, but many require additional training and many are unsuitable for older individuals, thus reducing their utility in lower/ middle- income countries. We aimed to derive a simpli...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062015/ https://www.ncbi.nlm.nih.gov/pubmed/33886585 http://dx.doi.org/10.1371/journal.pone.0249970 |
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author | Chakraborty, Satabdi Bhatia, Triptish Sharma, Vikas Antony, Nitin Das, Dhritishree Sahu, Sushree Sharma, Satyam Shriharsh, Vandana Brar, Jaspreet S. Iyengar, Satish Singh, Ravinder Nimgaonkar, Vishwajit L. Deshpande, Smita Neelkanth |
author_facet | Chakraborty, Satabdi Bhatia, Triptish Sharma, Vikas Antony, Nitin Das, Dhritishree Sahu, Sushree Sharma, Satyam Shriharsh, Vandana Brar, Jaspreet S. Iyengar, Satish Singh, Ravinder Nimgaonkar, Vishwajit L. Deshpande, Smita Neelkanth |
author_sort | Chakraborty, Satabdi |
collection | PubMed |
description | INTRODUCTION: Currently available screening questionnaires for Autism spectrum disorders were tested in developed countries, but many require additional training and many are unsuitable for older individuals, thus reducing their utility in lower/ middle- income countries. We aimed to derive a simplified questionnaire that could be used to screen persons in India. METHODS: We have previously validated Indian Scale for Assessment of Autism (ISAA), that is now mandated for disability assessment by the Government of India. This detailed tool requires intensive training and it is time consuming. It was used to derive a new screening questionnaire: 1) items most frequently scored as positive by participants with autism in original ISAA validation study were modified for binary scoring following expert review. 2) In a new sample, clinically diagnosed individuals with/without autism were administered the screening tool and ISAA following written informed consent. Its psychometric properties were determined. RESULTS: A 10-item scale named Indian Autism Screening Questionnaire (IASQ) was prepared in Hindi and English. Thereafter 145 parents/caregivers of participants (autism, n = 90, other psychiatric disorders, n = 55) (ages 3–18), were administered IASQ and ISAA (parents/caregivers plus observation) by separate interviewers, blind to each other and to diagnosis. At a cutoff of 1, sensitivity was 99%, specificity 62%, Positive Predictive Value 81%, and Negative Predictive Value 95%. Test-retest reliability was r = 0.767 (CI = 0.62–0.86) and interrater reliability- Krippendorff”s-alpha was 0.872. The area under Receiver Operating Characteristic Curve (ROC) was 95%. There was a significant difference on IASQ-scores between participants with and without a clinical diagnosis of Autism (t = 14.57, p<0.0001). DISCUSSION: The IASQ is a simple, easy to use screening tool with satisfactory reliability and validity, that can be administered to caregivers in 15 minutes and provides information about DSM 5 criteria for autism. It may be applicable outside India, following additional adaptation, for community-based studies. |
format | Online Article Text |
id | pubmed-8062015 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-80620152021-05-04 Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) Chakraborty, Satabdi Bhatia, Triptish Sharma, Vikas Antony, Nitin Das, Dhritishree Sahu, Sushree Sharma, Satyam Shriharsh, Vandana Brar, Jaspreet S. Iyengar, Satish Singh, Ravinder Nimgaonkar, Vishwajit L. Deshpande, Smita Neelkanth PLoS One Research Article INTRODUCTION: Currently available screening questionnaires for Autism spectrum disorders were tested in developed countries, but many require additional training and many are unsuitable for older individuals, thus reducing their utility in lower/ middle- income countries. We aimed to derive a simplified questionnaire that could be used to screen persons in India. METHODS: We have previously validated Indian Scale for Assessment of Autism (ISAA), that is now mandated for disability assessment by the Government of India. This detailed tool requires intensive training and it is time consuming. It was used to derive a new screening questionnaire: 1) items most frequently scored as positive by participants with autism in original ISAA validation study were modified for binary scoring following expert review. 2) In a new sample, clinically diagnosed individuals with/without autism were administered the screening tool and ISAA following written informed consent. Its psychometric properties were determined. RESULTS: A 10-item scale named Indian Autism Screening Questionnaire (IASQ) was prepared in Hindi and English. Thereafter 145 parents/caregivers of participants (autism, n = 90, other psychiatric disorders, n = 55) (ages 3–18), were administered IASQ and ISAA (parents/caregivers plus observation) by separate interviewers, blind to each other and to diagnosis. At a cutoff of 1, sensitivity was 99%, specificity 62%, Positive Predictive Value 81%, and Negative Predictive Value 95%. Test-retest reliability was r = 0.767 (CI = 0.62–0.86) and interrater reliability- Krippendorff”s-alpha was 0.872. The area under Receiver Operating Characteristic Curve (ROC) was 95%. There was a significant difference on IASQ-scores between participants with and without a clinical diagnosis of Autism (t = 14.57, p<0.0001). DISCUSSION: The IASQ is a simple, easy to use screening tool with satisfactory reliability and validity, that can be administered to caregivers in 15 minutes and provides information about DSM 5 criteria for autism. It may be applicable outside India, following additional adaptation, for community-based studies. Public Library of Science 2021-04-22 /pmc/articles/PMC8062015/ /pubmed/33886585 http://dx.doi.org/10.1371/journal.pone.0249970 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
spellingShingle | Research Article Chakraborty, Satabdi Bhatia, Triptish Sharma, Vikas Antony, Nitin Das, Dhritishree Sahu, Sushree Sharma, Satyam Shriharsh, Vandana Brar, Jaspreet S. Iyengar, Satish Singh, Ravinder Nimgaonkar, Vishwajit L. Deshpande, Smita Neelkanth Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title | Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title_full | Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title_fullStr | Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title_full_unstemmed | Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title_short | Psychometric properties of a screening tool for autism in the community—The Indian Autism Screening Questionnaire (IASQ) |
title_sort | psychometric properties of a screening tool for autism in the community—the indian autism screening questionnaire (iasq) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062015/ https://www.ncbi.nlm.nih.gov/pubmed/33886585 http://dx.doi.org/10.1371/journal.pone.0249970 |
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