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ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo

Over the past years, neutrophil extracellular traps (NETs) were shown to contribute to states of acute and chronic inflammatory disease. They are composed of expelled chromatin and decorated by neutrophil-derived proteins. Therefore, the analysis of DNA complexes with myeloperoxidase (MPO) by ELISA...

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Detalles Bibliográficos
Autores principales: Hayden, Hubert, Ibrahim, Nahla, Klopf, Johannes, Zagrapan, Branislav, Mauracher, Lisa-Marie, Hell, Lena, Hofbauer, Thomas M., Ondracek, Anna S., Schoergenhofer, Christian, Jilma, Bernd, Lang, Irene M., Pabinger, Ingrid, Eilenberg, Wolf, Neumayer, Christoph, Brostjan, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062102/
https://www.ncbi.nlm.nih.gov/pubmed/33886636
http://dx.doi.org/10.1371/journal.pone.0250265