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DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation
In mammals, cellular identity is defined through strict regulation of chromatin modifications and DNA methylation that control gene expression. Methylation of cytosines at CpG sites in the genome is mainly associated with suppression; however, the reason for enhancer-specific methylation is not full...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062104/ https://www.ncbi.nlm.nih.gov/pubmed/33844685 http://dx.doi.org/10.1371/journal.pgen.1009498 |