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DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation

In mammals, cellular identity is defined through strict regulation of chromatin modifications and DNA methylation that control gene expression. Methylation of cytosines at CpG sites in the genome is mainly associated with suppression; however, the reason for enhancer-specific methylation is not full...

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Detalles Bibliográficos
Autores principales: Alajem, Adi, Roth, Hava, Ratgauzer, Sofia, Bavli, Danny, Motzik, Alex, Lahav, Shlomtzion, Peled, Itay, Ram, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062104/
https://www.ncbi.nlm.nih.gov/pubmed/33844685
http://dx.doi.org/10.1371/journal.pgen.1009498