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Molecular basis of F-actin regulation and sarcomere assembly via myotilin

Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain-containing protein myotilin provides structural integrity to Z-discs—the boundaries between adjacent sarcome...

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Detalles Bibliográficos
Autores principales: Kostan, Julius, Pavšič, Miha, Puž, Vid, Schwarz, Thomas C., Drepper, Friedel, Molt, Sibylle, Graewert, Melissa Ann, Schreiner, Claudia, Sajko, Sara, van der Ven, Peter F. M., Onipe, Adekunle, Svergun, Dmitri I., Warscheid, Bettina, Konrat, Robert, Fürst, Dieter O., Lenarčič, Brigita, Djinović-Carugo, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062120/
https://www.ncbi.nlm.nih.gov/pubmed/33844684
http://dx.doi.org/10.1371/journal.pbio.3001148