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Whole-organism eQTL mapping at cellular resolution with single-cell sequencing

Genetic regulation of gene expression underlies variation in disease risk and other complex traits. The effect of expression quantitative trait loci (eQTLs) varies across cell types; however, the complexity of mammalian tissues makes studying cell-type eQTLs highly challenging. We developed a novel...

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Detalles Bibliográficos
Autores principales:	Ben-David, Eyal, Boocock, James, Guo, Longhua, Zdraljevic, Stefan, Bloom, Joshua S, Kruglyak, Leonid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062134/ https://www.ncbi.nlm.nih.gov/pubmed/33734084 http://dx.doi.org/10.7554/eLife.65857

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