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The cis-regulatory effects of modern human-specific variants

The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ between modern and archaic humans, the majority of which are noncoding. However, our understanding of the regulatory consequences of these differences remains limited, in part due to the decay of regulatory marks in...

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Detalles Bibliográficos
Autores principales: Weiss, Carly V, Harshman, Lana, Inoue, Fumitaka, Fraser, Hunter B, Petrov, Dmitri A, Ahituv, Nadav, Gokhman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062137/
https://www.ncbi.nlm.nih.gov/pubmed/33885362
http://dx.doi.org/10.7554/eLife.63713