Cargando…

Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses subgenomic RNA (sgRNA) to produce viral proteins for replication and immune evasion. We apply long-read RNA and cDNA sequencing to in vitro human and primate infection models to study transcriptional dynamics. Transcription-regulating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Jessie J.-Y., Rawlinson, Daniel, Pitt, Miranda E., Taiaroa, George, Gleeson, Josie, Zhou, Chenxi, Mordant, Francesca L., De Paoli-Iseppi, Ricardo, Caly, Leon, Purcell, Damian F.J., Stinear, Timothy P., Londrigan, Sarah L., Clark, Michael B., Williamson, Deborah A., Subbarao, Kanta, Coin, Lachlan J.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062406/ https://www.ncbi.nlm.nih.gov/pubmed/33961822 http://dx.doi.org/10.1016/j.celrep.2021.109108

Ejemplares similares

Long-Read RNA Sequencing Identifies Polyadenylation Elongation and Differential Transcript Usage of Host Transcripts During SARS-CoV-2 In Vitro Infection
por: Chang, Jessie J.-Y., et al.
Publicado: (2022)

Corrigendum: Isoform Age - Splice Isoform Profiling Using Long-Read Technologies
por: De Paoli-Iseppi, Ricardo, et al.
Publicado: (2021)

Isoform Age - Splice Isoform Profiling Using Long-Read Technologies
por: De Paoli-Iseppi, Ricardo, et al.
Publicado: (2021)

Pervasive effects of RNA degradation on Nanopore direct RNA sequencing
por: Prawer, Yair D J, et al.
Publicado: (2023)

No evidence of SARS-CoV-2 reverse transcription and integration as the origin of chimeric transcripts in patient tissues
por: Parry, Rhys, et al.
Publicado: (2021)

CRISPR–Cas-mediated transcriptional control and epi-mutagenesis
por: Gardiner, Jason, et al.
Publicado: (2022)

Multiomic chromatin and transcription profiling with EpiDamID
por: Gopalan, Sneha, et al.
Publicado: (2022)

Comparative Longitudinal Serological Study of Anti-SARS-CoV-2 Antibody Profiles in People with COVID-19
por: Barrios, Marilou H., et al.
Publicado: (2023)

Evaluation of 6 Commercial SARS-CoV-2 Serology Assays Detecting Different Antibodies for Clinical Testing and Serosurveillance
por: Nicholson, Suellen, et al.
Publicado: (2021)

SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in Mice
por: Baz, Mariana, et al.
Publicado: (2022)

Simulating the dynamics of targeted capture sequencing with CapSim
por: Cao, Minh Duc, et al.
Publicado: (2018)

Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data
por: Shao, Haojing, et al.
Publicado: (2018)

Suites and transcriptions for harpsichord.
por: Purcell, Henry, 1659-1695
Publicado: (1997)

Epi-fingerprinting and epi-interventions for improved crop production and food quality
por: Rodríguez López, Carlos M., et al.
Publicado: (2015)

Two Sides of the Same Coin: TFIIH Complexes in Transcription and DNA Repair
por: Zhovmer, Alexander, et al.
Publicado: (2010)

Maintaining genomic surveillance using whole-genome sequencing of SARS-CoV-2 from rapid antigen test devices
por: Martin, Genevieve E, et al.
Publicado: (2022)

Computational analysis and prediction of PE_PGRS proteins using machine learning
por: Li, Fuyi, et al.
Publicado: (2022)

Transcriptional and reverse transcriptional regulation of host genes by human endogenous retroviruses in cancers
por: Zhang, Mengwen, et al.
Publicado: (2022)

SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates
por: Bader, Stefanie M., et al.
Publicado: (2023)

True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair
por: Le May, Nicolas, et al.
Publicado: (2010)

Vaccines for Pandemic Influenza
por: Luke, Catherine J., et al.
Publicado: (2006)

The Role of Animal Models In Influenza Vaccine Research
por: Luke, Catherine J., et al.
Publicado: (2010)

The role of animal models in influenza vaccine research
por: Luke, Catherine J., et al.
Publicado: (2008)

Advances in Influenza Virus Research: A Personal Perspective
por: Subbarao, Kanta
Publicado: (2018)

The Critical Interspecies Transmission Barrier at the Animal–Human Interface
por: Subbarao, Kanta
Publicado: (2019)

SARS-CoV-2: A New Song Recalls an Old Melody
por: Subbarao, Kanta
Publicado: (2020)

The success of SARS-CoV-2 vaccines and challenges ahead
por: Subbarao, Kanta
Publicado: (2021)

Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era
por: Xie, Shangqian, et al.
Publicado: (2021)

cnvOffSeq: detecting intergenic copy number variation using off-target exome sequencing data
por: Bellos, Evangelos, et al.
Publicado: (2014)

Antibody titres elicited by the 2018 seasonal inactivated influenza vaccine decline by 3 months post‐vaccination but persist for at least 6 months
por: Mordant, Francesca L., et al.
Publicado: (2022)

The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells (†)
por: Miller, Matthew R., et al.
Publicado: (2022)

Analytical Sensitivity of Lateral Flow Devices against SARS-CoV-2 Omicron Subvariants BA.4, BA.5, and BA.2.75
por: Mackenzie, Charlene, et al.
Publicado: (2022)

Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay
por: Lopez, Ester, et al.
Publicado: (2021)

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function
por: Hemingway, Cheryl, et al.
Publicado: (2017)

TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
por: Compe, Emmanuel, et al.
Publicado: (2019)

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data
por: Bock, Christoph, et al.
Publicado: (2009)

ActivEpi companion textbook: a supplement for use with the ActivEpi CD-ROM
por: Kleinbaum, David G, et al.
Publicado: (2013)

Epi‐immunotherapy for cancers: rationales of epi‐drugs in combination with immunotherapy and advances in clinical trials
por: Xu, Yang, et al.
Publicado: (2022)

Comparison of single-shot EPI and multi-shot EPI in prostate DWI at 3.0 T
por: Tamada, Tsutomu, et al.
Publicado: (2022)

Respiratory Virus Vaccines
por: Broadbent, Andrew J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_f4riocp0qshsg9l4i2v61llbpk