Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?

Prothrombotic states, similar to heparin-induced thrombocytopenia (HIT) in recipients of the ChAdOx vaccine, sounded alarm bells internationally. Equivalent episodes of HIT were detailed in several case reports of coronavirus disease 2019. This suggests a common pathogenesis and warrants a shift in...

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Autores principales: AbdelMassih, A., Hozaien, R., El Shershaby, M., Kamel, A., Ismail, H-A, Fouda, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Hot Topic
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062416/
https://www.ncbi.nlm.nih.gov/pubmed/33907627
http://dx.doi.org/10.1016/j.nmni.2021.100884
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author AbdelMassih, A.
Hozaien, R.
El Shershaby, M.
Kamel, A.
Ismail, H-A
Fouda, R.
author_facet AbdelMassih, A.
Hozaien, R.
El Shershaby, M.
Kamel, A.
Ismail, H-A
Fouda, R.
author_sort AbdelMassih, A.
collection PubMed
description Prothrombotic states, similar to heparin-induced thrombocytopenia (HIT) in recipients of the ChAdOx vaccine, sounded alarm bells internationally. Equivalent episodes of HIT were detailed in several case reports of coronavirus disease 2019. This suggests a common pathogenesis and warrants a shift in the management of implicated cases.
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spelling pubmed-80624162021-04-23 Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases? AbdelMassih, A. Hozaien, R. El Shershaby, M. Kamel, A. Ismail, H-A Fouda, R. New Microbes New Infect Hot Topic Prothrombotic states, similar to heparin-induced thrombocytopenia (HIT) in recipients of the ChAdOx vaccine, sounded alarm bells internationally. Equivalent episodes of HIT were detailed in several case reports of coronavirus disease 2019. This suggests a common pathogenesis and warrants a shift in the management of implicated cases. Elsevier 2021-04-23 /pmc/articles/PMC8062416/ /pubmed/33907627 http://dx.doi.org/10.1016/j.nmni.2021.100884 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Hot Topic
AbdelMassih, A.
Hozaien, R.
El Shershaby, M.
Kamel, A.
Ismail, H-A
Fouda, R.
Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title_full Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title_fullStr Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title_full_unstemmed Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title_short Is the heparin-induced thrombocytopenia-like syndrome associated with ChAdOx vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
title_sort is the heparin-induced thrombocytopenia-like syndrome associated with chadox vaccine related to the vaccine itself or to an autoimmune reaction to severe acute respiratory syndrome 2 coronavirus: insights and implications from previous reports in infected cases?
topic Hot Topic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062416/
https://www.ncbi.nlm.nih.gov/pubmed/33907627
http://dx.doi.org/10.1016/j.nmni.2021.100884
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