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A prognostic value of CD45RA(+), CD45RO(+), CCL20(+) and CCR6(+) expressing cells as ‘immunoscore’ to predict cervical cancer induced by HPV

The interplay between cervical cancer (CC) and immune cells, mainly intratumoral lymphocytes, has a pivotal role in carcinogenesis. In this context, we evaluated the distribution of CD45RA(+) and CD45RO(+) cells as well as CCR6(+) and CCL20(+) cells in intraepithelial (IE) and marginal stroma (MS) a...

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Detalles Bibliográficos
Autores principales: Fernandes, Ana Teresa G., Carvalho, Maria Odete O., Avvad-Portari, Elyzabeth, Rocha, Natália P., Russomano, Fabio, Roma, Eric Henrique, Bonecini-Almeida, Maria da Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062468/
https://www.ncbi.nlm.nih.gov/pubmed/33888832
http://dx.doi.org/10.1038/s41598-021-88248-x