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C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition
The c subunit is an inner mitochondrial membrane (IMM) protein encoded by three nuclear genes. Best known as an integral part of the F(0) complex of the ATP synthase, the c subunit is also present in other cytoplasmic compartments in ceroid lipofuscinoses. Under physiological conditions, this 75 res...
Autores principales: | Amodeo, Giuseppe Federico, Lee, Brenda Yasie, Krilyuk, Natalya, Filice, Carina Teresa, Valyuk, Denis, Otzen, Daniel Erik, Noskov, Sergey, Leonenko, Zoya, Pavlov, Evgeny V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062469/ https://www.ncbi.nlm.nih.gov/pubmed/33888826 http://dx.doi.org/10.1038/s41598-021-88157-z |
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