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C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition

The c subunit is an inner mitochondrial membrane (IMM) protein encoded by three nuclear genes. Best known as an integral part of the F(0) complex of the ATP synthase, the c subunit is also present in other cytoplasmic compartments in ceroid lipofuscinoses. Under physiological conditions, this 75 res...

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Detalles Bibliográficos
Autores principales: Amodeo, Giuseppe Federico, Lee, Brenda Yasie, Krilyuk, Natalya, Filice, Carina Teresa, Valyuk, Denis, Otzen, Daniel Erik, Noskov, Sergey, Leonenko, Zoya, Pavlov, Evgeny V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062469/
https://www.ncbi.nlm.nih.gov/pubmed/33888826
http://dx.doi.org/10.1038/s41598-021-88157-z

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