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Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced antibodies to SIC are protective against inva...

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Detalles Bibliográficos
Autores principales:	Tan, Lionel K. K., Reglinski, Mark, Teo, Daryl, Reza, Nada, Lamb, Lucy E. M., Nageshwaran, Vaitehi, Turner, Claire E., Wikstrom, Mats, Frick, Inga-Maria, Bjorck, Lars, Sriskandan, Shiranee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062509/ https://www.ncbi.nlm.nih.gov/pubmed/33888727 http://dx.doi.org/10.1038/s41541-021-00326-3

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