Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration

Obesity is implicated in cardiovascular disease and heart failure. When fatty acids are transported to and not adequately oxidized in cardiac cells, they accumulate, causing lipotoxicity in the heart. Since hepatic progesterone receptor membrane component 1 (Pgrmc1) suppressed de novo lipogenesis in...

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Detalles Bibliográficos
Autores principales: Lee, Sang R., Heo, Jun H., Jo, Seong Lae, Kim, Globinna, Kim, Su Jung, Yoo, Hyun Ju, Lee, Kyu-Pil, Kwun, Hyo-Jung, Shin, Hyun-Jin, Baek, In-Jeoung, Hong, Eui-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062525/
https://www.ncbi.nlm.nih.gov/pubmed/33888830
http://dx.doi.org/10.1038/s41598-021-88251-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062525/
https://www.ncbi.nlm.nih.gov/pubmed/33888830
http://dx.doi.org/10.1038/s41598-021-88251-2

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