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Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo

Photoactivatable molecules enable ablation of malignant cells under the control of light, yet current agents can be ineffective at early stages of disease when target cells are similar to healthy surrounding tissues. In this work, we describe a chemical platform based on amino-substituted benzoselen...

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Detalles Bibliográficos
Autores principales: Benson, Sam, de Moliner, Fabio, Fernandez, Antonio, Kuru, Erkin, Asiimwe, Nicholas L., Lee, Jun-Seok, Hamilton, Lloyd, Sieger, Dirk, Bravo, Isabel R., Elliot, Abigail M., Feng, Yi, Vendrell, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062536/
https://www.ncbi.nlm.nih.gov/pubmed/33888691
http://dx.doi.org/10.1038/s41467-021-22578-2

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