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Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo
Photoactivatable molecules enable ablation of malignant cells under the control of light, yet current agents can be ineffective at early stages of disease when target cells are similar to healthy surrounding tissues. In this work, we describe a chemical platform based on amino-substituted benzoselen...
Autores principales: | Benson, Sam, de Moliner, Fabio, Fernandez, Antonio, Kuru, Erkin, Asiimwe, Nicholas L., Lee, Jun-Seok, Hamilton, Lloyd, Sieger, Dirk, Bravo, Isabel R., Elliot, Abigail M., Feng, Yi, Vendrell, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062536/ https://www.ncbi.nlm.nih.gov/pubmed/33888691 http://dx.doi.org/10.1038/s41467-021-22578-2 |
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