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Genetic variant rs10251977 (G>A) in EGFR-AS1 modulates the expression of EGFR isoforms A and D

Tyrosine kinase inhibitor is an effective chemo-therapeutic drug against tumors with deregulated EGFR pathway. Recently, a genetic variant rs10251977 (G>A) in exon 20 of EGFR reported to act as a prognostic marker for HNSCC. Genotyping of this polymorphism in oral cancer patients showed a similar...

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Detalles Bibliográficos
Autores principales:	Dhamodharan, Shankar, Rose, Mathew Maria, Chakkarappan, Sundaram Reddy, Umadharshini, Karuppiah Vijayamuthuramalingam, Arulmurugan, Ramalingam, Subbiah, Shanmugam, Inoue, Ituro, Munirajan, Arasambattu Kannan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062556/ https://www.ncbi.nlm.nih.gov/pubmed/33888812 http://dx.doi.org/10.1038/s41598-021-88161-3

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