Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders

The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic differences in AKs before and after treatment with...

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Detalles Bibliográficos
Autores principales: Trager, Megan H., Rizk, Emanuelle, Rose, Sharon, Zhu, Kuixi, Lau, Branden, Fullerton, Benjamin T., Pradhan, Jaya, Moore, Michael, Srivastava, Ayush C., Singer, Giselle, Gartrell, Robyn, Chang, Rui, Geskin, Larisa J., Saenger, Yvonne M., Goldenberg, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062619/
https://www.ncbi.nlm.nih.gov/pubmed/33888854
http://dx.doi.org/10.1038/s41598-021-88424-z

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