Cargando…

Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats

Hyperoxia-induced lung injury plays a key role in the development of bronchopulmonary dysplasia (BPD), characterized by inflammatory injury and impaired lung development in preterm infants. Although BPD is a predictor of poor neurodevelopmental outcomes, currently it is uncertain how lung injury con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ali, Anum, Zambrano, Ronald, Duncan, Matthew R., Chen, Shaoyi, Luo, Shihua, Yuan, Huijun, Chen, Pingping, Benny, Merline, Schmidt, Augusto, Young, Karen, Kerr, Nadine, de Rivero Vaccari, Juan Pablo, Keane, Robert W., Dietrich, W. Dalton, Wu, Shu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062626/ https://www.ncbi.nlm.nih.gov/pubmed/33888735 http://dx.doi.org/10.1038/s41598-021-87706-w

Ejemplares similares

Author Correction: Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats
por: Ali, Anum, et al.
Publicado: (2021)

GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice
por: Sonny, Sarah, et al.
Publicado: (2023)

GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
por: Challa, Naga Venkata Divya, et al.
Publicado: (2023)

GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
por: Challa, Naga Venkata Divya, et al.
Publicado: (2023)

Circulating extracellular vesicles activate the pyroptosis pathway in the brain following ventilation-induced lung injury
por: Chavez, Laura, et al.
Publicado: (2021)

Inflammasome Proteins in Serum and Serum-Derived Extracellular Vesicles as Biomarkers of Stroke
por: Kerr, Nadine, et al.
Publicado: (2018)

Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth
por: Donda, Keyur, et al.
Publicado: (2018)

Mesenchymal Stem Cell-derived Extracellular Vesicles Prevent Experimental Bronchopulmonary Dysplasia Complicated By Pulmonary Hypertension
por: Sharma, Mayank, et al.
Publicado: (2022)

Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats
por: Benny, Merline, et al.
Publicado: (2020)

Extracellular vesicles: pathogenic messengers and potential therapy for neonatal lung diseases
por: Wu, Shu, et al.
Publicado: (2023)

The Inflammasome in Times of COVID-19
por: de Rivero Vaccari, Juan Carlos, et al.
Publicado: (2020)

Inflammasome Proteins As Biomarkers of Multiple Sclerosis
por: Keane, Robert W., et al.
Publicado: (2018)

Human Lung Cell Pyroptosis Following Traumatic Brain Injury
por: Kerr, Nadine A., et al.
Publicado: (2019)

Protective role of CXCR7 activation in neonatal hyperoxia-induced systemic vascular remodeling and cardiovascular dysfunction in juvenile rats
por: Benny, Merline, et al.
Publicado: (2023)

Inflammasome proteins as biomarkers of traumatic brain injury
por: Kerr, Nadine, et al.
Publicado: (2018)

The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury
por: Lee, Stephanie W., et al.
Publicado: (2019)

Inflammasome activation in traumatic brain injury and Alzheimer’s disease
por: Johnson, Nathan H., et al.
Publicado: (2023)

RIG-1 receptor expression in the pathology of Alzheimer’s disease
por: de Rivero Vaccari, Juan Pablo, et al.
Publicado: (2014)

The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer’s Disease
por: Scott, Xavier O., et al.
Publicado: (2020)

Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease
por: Vontell, Regina T., et al.
Publicado: (2022)

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia
por: Reis, Monica, et al.
Publicado: (2021)

IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis
por: Desu, Haritha L., et al.
Publicado: (2020)

Deep Tissue Injury in Development of Pressure Ulcers: A Decrease of Inflammasome Activation and Changes in Human Skin Morphology in Response to Aging and Mechanical Load
por: Stojadinovic, Olivera, et al.
Publicado: (2013)

Aerosolized Human Extracellular Superoxide Dismutase Prevents Hyperoxia-Induced Lung Injury
por: Yen, Chih-Ching, et al.
Publicado: (2011)

Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets
por: Govindarajan, Vaidya, et al.
Publicado: (2020)

ASC, IL-18 and Galectin-3 as Biomarkers of Non-Alcoholic Steatohepatitis: A Proof of Concept Study
por: Cyr, Brianna, et al.
Publicado: (2020)

Inflammasome signaling proteins as biomarkers of COVID-19
por: Hadad, Roey, et al.
Publicado: (2023)

Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia
por: Buczynski, Bradley W., et al.
Publicado: (2018)

Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia
por: Guerra, Kasonya, et al.
Publicado: (2019)

Dangers of hyperoxia
por: Singer, Mervyn, et al.
Publicado: (2021)

Hyperoxia in depression
por: Belmaker, R., et al.
Publicado: (2021)

Renal and Inflammatory Proteins as Biomarkers of Diabetic Kidney Disease and Lupus Nephritis
por: Johnson, Nathan H., et al.
Publicado: (2022)

Low-Dose Vitamin D Protects Hyperoxia-Induced Bronchopulmonary Dysplasia by Inhibiting Neutrophil Extracellular Traps
por: Chen, Cuie, et al.
Publicado: (2020)

The Inflammasome Signaling Proteins ASC and IL-18 as Biomarkers of Psoriasis
por: Forouzandeh, Mahtab, et al.
Publicado: (2020)

The Role of Non-canonical and Canonical Inflammasomes in Inflammaging
por: Cyr, Brianna, et al.
Publicado: (2022)

Oxygen Variations—Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia—Is the Dose the Clue?
por: Balestra, Costantino, et al.
Publicado: (2023)

Netosis and Inflammasomes in Large Vessel Occlusion Thrombi
por: Chen, Stephanie H., et al.
Publicado: (2021)

Inflammatory Biomarkers of Traumatic Brain Injury
por: Johnson, Nathan H., et al.
Publicado: (2022)

Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy
por: Fuhrmann, Gregor, et al.
Publicado: (2018)

Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury
por: Willis, Gareth R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_55nsuejj4h4d7ihu2dmbs8n1bs