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Increased expression of peptides from non-coding genes in cancer proteomics datasets suggests potential tumor neoantigens

Neoantigen-based immunotherapy has yielded promising results in clinical trials. However, it is limited to tumor-specific mutations, and is often tailored to individual patients. Identifying suitable tumor-specific antigens is still a major challenge. Previous proteogenomics studies have identified...

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Detalles Bibliográficos
Autores principales: Xiang, Rong, Ma, Leyao, Yang, Mingyu, Zheng, Zetian, Chen, Xiaofang, Jia, Fujian, Xie, Fanfan, Zhou, Yiming, Li, Fuqiang, Wu, Kui, Zhu, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062694/
https://www.ncbi.nlm.nih.gov/pubmed/33888849
http://dx.doi.org/10.1038/s42003-021-02007-2